Urothelial carcinoma of the urethra: Difference between revisions
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Urothelial carcinoma in prostate - 2 -- high mag.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Urothelial carcinoma and benign prostatic tissue in keeping with urethral urothelial carcinoma. [[H&E stain]]. (WC/Nephron) | ||
| Synonyms = | | Synonyms = | ||
| Micro = | | Micro = | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = [[prostatic carcinoma]] - especially poorly differentiated and [[urothelial carcinoma-like prostatic carcinoma]] | ||
| Stains = | | Stains = [[GATA3]] +ve, [[p63]] +ve, CK5/6 +ve, [[PSA]] -ve, [[PSAP]] -ve | ||
| IHC = | | IHC = | ||
| EM = | | EM = | ||
| Line 14: | Line 14: | ||
| IF = | | IF = | ||
| Gross = | | Gross = | ||
| Grossing = | | Grossing = [[cystoprostatectomy grossing]], [[TURP grossing]] | ||
| Staging = | | Staging = | ||
| Site = [[urethra]] - also see [[prostate]] ([[prostate cancer]]) | | Site = [[urethra]] - also see [[prostate]] ([[prostate cancer]]) | ||
| Line 20: | Line 20: | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = +/-radiation therapy, [[bladder cancer]] | | Clinicalhx = +/-radiation therapy, [[bladder cancer]] | ||
| Signs = | | Signs = +/-[[hematuria]] | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = uncommon | | Prevalence = uncommon | ||
| Line 28: | Line 28: | ||
| Prognosis = | | Prognosis = | ||
| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = benign urethral stricture | ||
| Tx = [[ | | Tx = [[cystoprostatectomy]]/cystectomy or endoscopic resection | ||
}} | }} | ||
'''Urothelial carcinoma of the urethra''' is an uncommon epithelial [[malignancy]] of the [[urethra]]. It may be primary, i.e. arises in the urethra, or secondary (spreads from the bladder or upper genitourinary tract). | '''Urothelial carcinoma of the urethra''' is an uncommon epithelial [[malignancy]] of the [[urethra]]. It may be primary, i.e. arises in the urethra, or secondary (spreads from the bladder or upper genitourinary tract). | ||
'''Prostatic urothelial carcinoma''' and '''urothelial carcinoma of the prostate gland''' redirect here. | '''Prostatic urothelial carcinoma''' and '''urothelial carcinoma of the prostate gland''' redirect here. | ||
''[[Distal urethral cancers of the penis]]'' are dealt with separately. | |||
==General== | ==General== | ||