Difference between revisions of "Adenovirus appendicitis"

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#redirect [[Vermiform appendix#Adenovirus appendicitis]]
'''Adenovirus appendicitis''' is a rare inflammatory condition of the [[appendix]].
 
==General==
*Rare type of appendicitis in children.
*Classically found in association with intussusception or mesenteric adenitis .
**Uncommonly presents as an [[acute appendicitis]].<ref name=pmid17990936>{{Cite journal  | last1 = Grynspan | first1 = D. | last2 = Rabah | first2 = R. | title = Adenoviral appendicitis presenting clinically as acute appendicitis. | journal = Pediatr Dev Pathol | volume = 11 | issue = 2 | pages = 138-41 | month =  | year = 2008 | doi = 10.2350/07-06-0299.1 | PMID = 17990936 }}</ref>
*Caused by ''[[Adenovirus]]''.
 
==Microscopic==
Features:<ref name=pmid17990936>{{Cite journal  | last1 = Grynspan | first1 = D. | last2 = Rabah | first2 = R. | title = Adenoviral appendicitis presenting clinically as acute appendicitis. | journal = Pediatr Dev Pathol | volume = 11 | issue = 2 | pages = 138-41 | month =  | year = 2008 | doi = 10.2350/07-06-0299.1 | PMID = 17990936 }}</ref>
*Lymphoid hyperplasia - key feature.
*+/-Adenovirus inclusions; "smudge cells".
 
Notes:
*The classic finding of appendicitis (neutrophils infiltrating into the muscularis propria) may be absent.<ref name=pmid17990936/>
 
DDx:
*[[Negative appendectomy]]
 
===Image===
*[http://wiki.medpedia.com/Image:Ab14.jpg?filetimestamp=20091014175858 Smudge cell (medpedia.com)].
 
==IHC==
*Adenovirus +ve = '''diagnostic'''.
 
==See also==
*[[Vermiform appendix]].
*[[Acute appendicitis]].
 
==References==
{{Reflist|1}}
 
[[Category:Diagnosis]]
[[Category:Vermiform appendix]]

Latest revision as of 21:01, 30 April 2019

Adenovirus appendicitis is a rare inflammatory condition of the appendix.

General

  • Rare type of appendicitis in children.
  • Classically found in association with intussusception or mesenteric adenitis .
  • Caused by Adenovirus.

Microscopic

Features:[1]

  • Lymphoid hyperplasia - key feature.
  • +/-Adenovirus inclusions; "smudge cells".

Notes:

  • The classic finding of appendicitis (neutrophils infiltrating into the muscularis propria) may be absent.[1]

DDx:

Image

IHC

  • Adenovirus +ve = diagnostic.

See also

References

  1. 1.0 1.1 1.2 Grynspan, D.; Rabah, R. (2008). "Adenoviral appendicitis presenting clinically as acute appendicitis.". Pediatr Dev Pathol 11 (2): 138-41. doi:10.2350/07-06-0299.1. PMID 17990936.