Difference between revisions of "Adenovirus appendicitis"
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*Rare type of appendicitis in children. | *Rare type of appendicitis in children. | ||
*Classically found in association with intussusception or mesenteric adenitis . | *Classically found in association with intussusception or mesenteric adenitis . | ||
**Uncommonly presents as an [[acute appendicitis]].<ref name=pmid17990936>{{Cite journal | last1 = Grynspan | first1 = D. | last2 = Rabah | first2 = R. | title = Adenoviral appendicitis presenting clinically as acute appendicitis. | journal = Pediatr Dev Pathol | volume = 11 | issue = 2 | pages = 138-41 | month = | year = | **Uncommonly presents as an [[acute appendicitis]].<ref name=pmid17990936>{{Cite journal | last1 = Grynspan | first1 = D. | last2 = Rabah | first2 = R. | title = Adenoviral appendicitis presenting clinically as acute appendicitis. | journal = Pediatr Dev Pathol | volume = 11 | issue = 2 | pages = 138-41 | month = | year = 2008 | doi = 10.2350/07-06-0299.1 | PMID = 17990936 }}</ref> | ||
*Caused by ''[[Adenovirus]]''. | *Caused by ''[[Adenovirus]]''. | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid17990936>{{ | Features:<ref name=pmid17990936>{{Cite journal | last1 = Grynspan | first1 = D. | last2 = Rabah | first2 = R. | title = Adenoviral appendicitis presenting clinically as acute appendicitis. | journal = Pediatr Dev Pathol | volume = 11 | issue = 2 | pages = 138-41 | month = | year = 2008 | doi = 10.2350/07-06-0299.1 | PMID = 17990936 }}</ref> | ||
*Lymphoid hyperplasia - key feature. | *Lymphoid hyperplasia - key feature. | ||
*+/-Adenovirus inclusions; "smudge cells". | *+/-Adenovirus inclusions; "smudge cells". | ||
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*The classic finding of appendicitis (neutrophils infiltrating into the muscularis propria) may be absent.<ref name=pmid17990936/> | *The classic finding of appendicitis (neutrophils infiltrating into the muscularis propria) may be absent.<ref name=pmid17990936/> | ||
Image | DDx: | ||
*[[Negative appendectomy]] | |||
===Image=== | |||
*[http://wiki.medpedia.com/Image:Ab14.jpg?filetimestamp=20091014175858 Smudge cell (medpedia.com)]. | *[http://wiki.medpedia.com/Image:Ab14.jpg?filetimestamp=20091014175858 Smudge cell (medpedia.com)]. | ||
Latest revision as of 21:01, 30 April 2019
Adenovirus appendicitis is a rare inflammatory condition of the appendix.
General
- Rare type of appendicitis in children.
- Classically found in association with intussusception or mesenteric adenitis .
- Uncommonly presents as an acute appendicitis.[1]
- Caused by Adenovirus.
Microscopic
Features:[1]
- Lymphoid hyperplasia - key feature.
- +/-Adenovirus inclusions; "smudge cells".
Notes:
- The classic finding of appendicitis (neutrophils infiltrating into the muscularis propria) may be absent.[1]
DDx:
Image
IHC
- Adenovirus +ve = diagnostic.