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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Increase in size & number of glands + | *Increase in size & number of glands + irregular shape. | ||
*Cell stratification. | *Cell stratification. | ||
*Nuclear enlargement. | *Nuclear enlargement. | ||
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Notes: | Notes: | ||
*Normal | *Normal "gland-to-stroma ratio" is 1:3. | ||
*Two "touching" glands may be one gland in section. | |||
Image: | Image: | ||
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[[Endometrial carcinoma]] vs. complex endometrial hyperplasia: | [[Endometrial carcinoma]] vs. complex endometrial hyperplasia: | ||
*Complex endometrial hyperplasia: non-confluent (glands distinct from one another). | *Complex endometrial hyperplasia: non-confluent (glands distinct from one another). | ||
* | *Endometrial carcinoma - one of the following:<ref name=Ref_GP239>{{Ref GP|239}}</ref> | ||
*#Cribriform architecture. | |||
*#Desmoplastic stromal response. | |||
*#Extensive papillary pattern. | |||
*#Stroma replaced by squamous epithelium. | |||
==Complex endometrial hyperplasia with atypia== | ==Complex endometrial hyperplasia with atypia== |
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