Difference between revisions of "Endometrial hyperplasia"

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(re-arrange, subdivide/split)
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*Nuclear enlargement.
*Nuclear enlargement.
*Mitoses common.
*Mitoses common.
*May occur with atypia.
*No nuclear atypia.


Notes:  
Notes:  
*Normal ''gland-to-stroma ratio'' is 1:3.
*Normal ''gland-to-stroma ratio'' is 1:3.


Images:
Image:
*[http://www.webpathology.com/image.asp?n=1&Case=568 Endometrial hyperplasia (webpathology.com)].
*[http://www.webpathology.com/image.asp?n=1&Case=568 Endometrial hyperplasia (webpathology.com)].
*[http://www.webpathology.com/image.asp?n=2&Case=568 Complex endometrial hyperplasia with atypia (webpathology.com)].


[[Endometrial carcinoma]] vs. complex endometrial hyperplasia:
[[Endometrial carcinoma]] vs. complex endometrial hyperplasia:
*Complex endometrial hyperplasia: non-confluent (glands distinct from one another).
*Complex endometrial hyperplasia: non-confluent (glands distinct from one another).
*Diagnosis of complex EH is based on histology (cytologic features).
*Diagnosis of complex EH is based on histology (cytologic features).
==Complex endometrial hyperplasia with atypia==
===Microscopic===
Features:
*Increase in size & number of glands + irreg. shape.
**Need cribriform architecture.
**Two "touching" glands are likely one gland in section.
*Cell stratification.
*Nuclear enlargement.
*Mitoses common.
*Nuclear atypia present.
Image:
*[http://www.webpathology.com/image.asp?n=2&Case=568 Complex endometrial hyperplasia with atypia (webpathology.com)].


=See also=
=See also=
48,524

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