Epididymis: Difference between revisions
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The '''epididymis''' is a mostly forgotten organ associated with the [[testis]]. It is rarely afflicited by tumours.<ref name=pmid22522502>{{Cite journal | last1 = Yeung | first1 = CH. | last2 = Wang | first2 = K. | last3 = Cooper | first3 = TG. | title = Why are epididymal tumours so rare? | journal = Asian J Androl | volume = 14 | issue = 3 | pages = 465-75 | month = May | year = 2012 | doi = 10.1038/aja.2012.20 | PMID = 22522502 }}</ref> | The '''epididymis''' is a mostly forgotten organ associated with the [[testis]]. It is rarely afflicited by tumours.<ref name=pmid22522502>{{Cite journal | last1 = Yeung | first1 = CH. | last2 = Wang | first2 = K. | last3 = Cooper | first3 = TG. | title = Why are epididymal tumours so rare? | journal = Asian J Androl | volume = 14 | issue = 3 | pages = 465-75 | month = May | year = 2012 | doi = 10.1038/aja.2012.20 | PMID = 22522502 }}</ref> | ||
==Normal histology== | ==Normal histology== | ||
Features: | Features: | ||
*Tubular structures lined by a pseudostratified epithelium with cilia. | *Tubular structures lined by a pseudostratified epithelium with cilia. | ||
Note: | |||
*Epididymis may have clear luminal cells focally. | |||
===Images=== | ===Images=== | ||
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Image:Epididymis_high_mag.jpg |[[Micrograph]] of an epididymis. [[H&E stain]]. | Image:Epididymis_high_mag.jpg |[[Micrograph]] of an epididymis. [[H&E stain]]. | ||
</gallery> | </gallery> | ||
==IHC== | |||
The epididymis' luminal cells stain with: | |||
*CK7 (diffuse). | |||
*p63 (patchy). | |||
Note: | |||
*Clear cells are may be seen; they are NEGATIVE for D2-40, PLAP and CD117. | |||
==Pathology== | ==Pathology== | ||
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*[[Serous cystadenoma]] of the epididymis.<ref name=pmid17318978>{{Cite journal | last1 = Klimis | first1 = T. | last2 = Vlahos | first2 = P. | last3 = Kokotas | first3 = N. | title = Serous cystadenoma of the epididymis of common epithelial ovarian type: case report with an immunohistochemical study. | journal = J BUON | volume = 11 | issue = 2 | pages = 237-40 | month = | year = | doi = | PMID = 17318978 }}</ref> | *[[Serous cystadenoma]] of the epididymis.<ref name=pmid17318978>{{Cite journal | last1 = Klimis | first1 = T. | last2 = Vlahos | first2 = P. | last3 = Kokotas | first3 = N. | title = Serous cystadenoma of the epididymis of common epithelial ovarian type: case report with an immunohistochemical study. | journal = J BUON | volume = 11 | issue = 2 | pages = 237-40 | month = | year = | doi = | PMID = 17318978 }}</ref> | ||
*[[Fibrous pseudotumour of the paratesticular region]] - uncommonly associated with the epididymis. | *[[Fibrous pseudotumour of the paratesticular region]] - uncommonly associated with the epididymis. | ||
*[[Epididymal cyst]]. | |||
==See also== | ==See also== | ||