Difference between revisions of "Gynecomastoid hyperplasia"

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#redirect [[Breast_pathology#Gynecomastoid_hyperplasia]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Gynecomastoid_hyperplasia_-_very_high_mag.jpg
| Width      =
| Caption    = Gynecomastoid hyperplasia. [[H&E stain]].
| Synonyms  = gynecomastia
| Micro      = moderate hyperplasia - glands have more than 2 cell layers, "budding"  (cells jut into the lumen, buds may be multicellular -- but narrower toward the centre of the lumen), stromal palor
| Subtypes  =
| LMDDx      = [[Micropapillary DCIS]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[breast]]
| Assdx      = [[Liver]] failure, [[Klinefelter syndrome]], testicular estrogen-producing [[germ cell tumour]] 
| Syndromes  =
| Clinicalhx =
| Signs      = excessive breast tissue
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        = surgery
}}
'''Gynecomastoid hyperplasia''', also '''gynecomastia''', is a benign [[breast pathology|pathology of the breast]] classically seen in young men.
 
==General==
*Benign enlargement of breasts in males.
**Histologic changes may be seen in females.<ref name=stony03>URL: [http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm]. Accessed on: 16 November 2011.</ref>
 
May be seen in the context of:
*[[Liver]] failure.
*[[Klinefelter syndrome]].
*Testicular estrogen-producing [[germ cell tumour]]. 
 
==Gross==
*Excessive breast tissue in males.
 
===Images===
<gallery>
Image:Gynecomastia 001.jpg | Gynecomastia. (WC)
Image:GynecomastiaFrontalAsymSevere.jpg | Gynecomastia - before and after. (WC)
</gallery>
 
==Microscopic==
Features:<ref name=stony03>URL: [http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm]. Accessed on: 16 November 2011.</ref>
*Moderate hyperplasia.
**Glands have more than 2 cell layers.
*"Budding" - individual cells jut into the lumen - '''key feature'''.
**Buds may be multicellular; however, narrower toward the centre of the lumen.
*Stromal palor.<ref>URL: [http://radiology.uchc.edu/eAtlas/Breast/1693.htm http://radiology.uchc.edu/eAtlas/Breast/1693.htm]. Accessed on: 16 November 2011.</ref>
 
DDx:
*[[Micropapillary DCIS]] - buds not narrower toward the centre of the lumen.
 
===Images===
<gallery>
Image:Gynecomastoid_hyperplasia_-_intermed_mag.jpg | Gynecomastoid hyperplasia - intermed. mag. (WC/Nephron)
Image:Gynecomastoid_hyperplasia_-_very_high_mag.jpg | Gynecomastoid hyperplasia - very high mag. (WC/Nephron)
Image:Gynecomastoid_hyperplasia_-2-_intermed_mag.jpg | Gynecomastoid hyperplasia - 2 - intermed. mag. (WC/Nephron)
</gallery>
www:
*[http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm Gynecomastoid hyperplasia (stonybrook.edu)].
*[http://radiology.uchc.edu/eAtlas/Breast/1693.htm Gynecomastia (radiology.uchc.edu)].
 
==Sign out==
<pre>
A. Breast Tissue (60 g), Right, Excision:
- Benign breast tissue.
 
B. Breast Tissue (70 g), Left, Excision:
- Benign breast tissue.
</pre>
 
===Alternate===
<pre>
Left Chest Mass, Excision:
- Breast tissue with gynecomastoid hyperplasia.
- NEGATIVE for malignancy.
</pre>
 
===Micro===
The sections show breast tissue with epithelial hyperplasia and stromal palor. The architecture is normal. Epithelial budding is present. Significant atypia is absent.
 
==See also==
*[[Breast pathology]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Breast pathology]]

Latest revision as of 21:24, 16 November 2022

Gynecomastoid hyperplasia
Diagnosis in short

Gynecomastoid hyperplasia. H&E stain.
Synonyms gynecomastia
LM moderate hyperplasia - glands have more than 2 cell layers, "budding" (cells jut into the lumen, buds may be multicellular -- but narrower toward the centre of the lumen), stromal palor
LM DDx Micropapillary DCIS
Site breast
Associated Dx Liver failure, Klinefelter syndrome, testicular estrogen-producing germ cell tumour
Signs excessive breast tissue
Prognosis benign
Treatment surgery

Gynecomastoid hyperplasia, also gynecomastia, is a benign pathology of the breast classically seen in young men.

General

  • Benign enlargement of breasts in males.
    • Histologic changes may be seen in females.[1]

May be seen in the context of:

Gross

  • Excessive breast tissue in males.

Images

  • Gynecomastia. (WC)

  • Gynecomastia - before and after. (WC)

Microscopic

Features:[1]

  • Moderate hyperplasia.
    • Glands have more than 2 cell layers.
  • "Budding" - individual cells jut into the lumen - key feature.
    • Buds may be multicellular; however, narrower toward the centre of the lumen.
  • Stromal palor.[2]

DDx:

Images

  • Gynecomastoid hyperplasia - intermed. mag. (WC/Nephron)

  • Gynecomastoid hyperplasia - very high mag. (WC/Nephron)

  • Gynecomastoid hyperplasia - 2 - intermed. mag. (WC/Nephron)

www:

Sign out

A. Breast Tissue (60 g), Right, Excision:
- Benign breast tissue.

B. Breast Tissue (70 g), Left, Excision:
- Benign breast tissue.

Alternate

Left Chest Mass, Excision:
- Breast tissue with gynecomastoid hyperplasia.
- NEGATIVE for malignancy.

Micro

The sections show breast tissue with epithelial hyperplasia and stromal palor. The architecture is normal. Epithelial budding is present. Significant atypia is absent.

See also

References

  1. ↑ 1.0 1.1 URL: http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm. Accessed on: 16 November 2011.
  2. ↑ URL: http://radiology.uchc.edu/eAtlas/Breast/1693.htm. Accessed on: 16 November 2011.
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