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Difference between revisions of "Crizotinib"
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*Lung carcinoma with MET amplification.<ref>{{Cite journal | last1 = Forde | first1 = PM. | last2 = Rudin | first2 = CM. | title = Crizotinib in the treatment of non-small-cell lung cancer. | journal = Expert Opin Pharmacother | volume = 13 | issue = 8 | pages = 1195-201 | month = Jun | year = 2012 | doi = 10.1517/14656566.2012.688029 | PMID = 22594847 }}</ref> | *Lung carcinoma with MET amplification.<ref>{{Cite journal | last1 = Forde | first1 = PM. | last2 = Rudin | first2 = CM. | title = Crizotinib in the treatment of non-small-cell lung cancer. | journal = Expert Opin Pharmacother | volume = 13 | issue = 8 | pages = 1195-201 | month = Jun | year = 2012 | doi = 10.1517/14656566.2012.688029 | PMID = 22594847 }}</ref> | ||
Crizotinib has been largely subplanted by | Crizotinib has been largely subplanted by newer ALK inhibitors (ceritinib, brigatinib, lorlatinib) that were designed to cross the blood-brain barrier.<ref name=pmid31331844>{{Cite journal | last1 = Wrona | first1 = A. | title = Management of CNS disease in ALK-positive non-small cell lung cancer: Is whole brain radiotherapy still needed? | journal = Cancer Radiother | volume = 23 | issue = 5 | pages = 432-438 | month = Sep | year = 2019 | doi = 10.1016/j.canrad.2019.03.009 | PMID = 31331844 }}</ref> | ||
==See also== | ==See also== | ||