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Difference between revisions of "Radiation esophagitis"
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'''Radiation esophagitis''' is a relatively uncommon pathology of the [[esophagus]] seen in the context of radiation treatments for thoracic malignancies. | '''Radiation esophagitis''' is a relatively uncommon pathology of the [[esophagus]], typically seen in the context of radiation treatments for thoracic [[cancer|malignancies]]. | ||
==General== | ==General== | ||
*Uncommon ~1% of patients getting radiation.<ref name=pmid26030254>{{Cite journal | last1 = Murro | first1 = D. | last2 = Jakate | first2 = S. | title = Radiation esophagitis. | journal = Arch Pathol Lab Med | volume = 139 | issue = 6 | pages = 827-30 | month = Jun | year = 2015 | doi = 10.5858/arpa.2014-0111-RS | PMID = 26030254 }}</ref> | *Uncommon ~1% of patients getting (thoracic) radiation.<ref name=pmid26030254>{{Cite journal | last1 = Murro | first1 = D. | last2 = Jakate | first2 = S. | title = Radiation esophagitis. | journal = Arch Pathol Lab Med | volume = 139 | issue = 6 | pages = 827-30 | month = Jun | year = 2015 | doi = 10.5858/arpa.2014-0111-RS | PMID = 26030254 }}</ref> | ||
==Gross/endoscopic== | |||
Features: | |||
*Erythema - nonspecific.<ref name=pmid26030254/> | |||
==Microscopic== | |||
Features:<ref name=pmid26030254/> | |||
*Variable inflammation. | |||
*Radiation-related [[nuclear atypia]] - endothelial cells and stromal cells. | |||
DDx: | |||
*[[Cytomegalovirus]]. | |||
==IHC== | |||
*[[CMV]] -ve. | |||
==Sign out== | ==Sign out== | ||
<pre> | <pre> | ||
Esophagus, 25 cm, Biopsy: | Esophagus, 25 cm, Biopsy: | ||