Difference between revisions of "Biphenotypic sinonasal sarcoma"
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'''Biphenotypic sinonasal sarcoma''' is a rare bland appearing [[cancer|malignant]] tumour of the [[head and neck pathology|head and neck]]. | '''Biphenotypic sinonasal sarcoma''', abbreviated '''SNS''',<ref name=pmid24859338/> is a rare bland appearing [[cancer|malignant]] tumour of the [[head and neck pathology|head and neck]]. | ||
It is also known as '''low grade sinonasla sarcoma with neural and myogenic features''', abbreviated '''LGSSNMF'''. | It is also known as '''low grade sinonasla sarcoma with neural and myogenic features''', abbreviated '''LGSSNMF'''. | ||
Revision as of 16:08, 13 March 2016
Biphenotypic sinonasal sarcoma, abbreviated SNS,[1] is a rare bland appearing malignant tumour of the head and neck.
It is also known as low grade sinonasla sarcoma with neural and myogenic features, abbreviated LGSSNMF.
General
- Rare.
- Female predominant.
Microscopic
Features;
- Bland hypercellular stroma typically without many mitoses.
- Invaginating glandular epithelium.
DDx:
IHC
- Actin +ve.
- S-100 +ve (strong).
Molecular
- PAX3-MAML3 fusion - t(2;4)(q35;q31.1).[1]