Difference between revisions of "Cronkhite-Canada syndrome"
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'''Cronkhite-Canada_syndrome''', abbreviated '''CCS''', is a very rare syndrome with [[hamartomatous polyps]] and ectodermal abnormalities. | |||
==General== | |||
Clinical features:<ref>{{Ref PBoD|858-9}}</ref> | |||
*Hamartomatous polyps. | |||
*Ectodermal abnormalities (nail atrophy, skin pigment, alopecia). | |||
==Microscopic== | |||
Features: | |||
*Polyps have same morphology as [[juvenile polyp]]s/retension polyps. | |||
*Crypt dilation and edema in non-polypoid mucosa<ref>{{Ref PCPBoD8|430}}</ref> - '''key feature'''. | |||
DDx: | |||
*[[Juvenile polyp]]. | |||
===Images=== | |||
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20090508151729401 CCS (surgicalpathologyatlas.com)]. | |||
==See also== | |||
*[[Gastrointestinal tracts polyps]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Gastrointestinal pathology]] | |||
Revision as of 17:07, 6 September 2014
Cronkhite-Canada_syndrome, abbreviated CCS, is a very rare syndrome with hamartomatous polyps and ectodermal abnormalities.
General
Clinical features:[1]
- Hamartomatous polyps.
- Ectodermal abnormalities (nail atrophy, skin pigment, alopecia).
Microscopic
Features:
- Polyps have same morphology as juvenile polyps/retension polyps.
- Crypt dilation and edema in non-polypoid mucosa[2] - key feature.
DDx:
Images
See also
References
- ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 858-9. ISBN 0-7216-0187-1.
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 430. ISBN 978-1416054542.