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Difference between revisions of "Solitary fibrous tumour of the pleura"
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Solitary fibrous tumour of the pleura (view source)
Revision as of 20:51, 20 February 2014
, 20:51, 20 February 2014no edit summary
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==General== | ==General== | ||
*Uncommon overall.<ref name= | *Uncommon overall<ref name=pmid24326857/> ~ 800 cases reported.<ref name=pmid17075563>{{Cite journal | last1 = Robinson | first1 = LA. | title = Solitary fibrous tumor of the pleura. | journal = Cancer Control | volume = 13 | issue = 4 | pages = 264-9 | month = Oct | year = 2006 | doi = | PMID = 17075563 }}</ref> | ||
**Common for the anatomical site. | **Common for the anatomical site. | ||
*Usually benign. | *Usually benign ~ 80% of the time.<ref name=pmid17075563/> | ||
*Slow growing.<ref name=pmid24326857>{{Cite journal | last1 = Mordenti | first1 = P. | last2 = Di Cicilia | first2 = R. | last3 = Delfanti | first3 = R. | last4 = Capelli | first4 = P. | last5 = Paties | first5 = C. | last6 = Cavanna | first6 = L. | title = Solitary fibrous tumors of the pleura: a case report and review of the literature. | journal = Tumori | volume = 99 | issue = 4 | pages = e177-83 | month = | year = | doi = 10.1700/1361.15120 | PMID = 24326857 }}</ref> | *Slow growing.<ref name=pmid24326857>{{Cite journal | last1 = Mordenti | first1 = P. | last2 = Di Cicilia | first2 = R. | last3 = Delfanti | first3 = R. | last4 = Capelli | first4 = P. | last5 = Paties | first5 = C. | last6 = Cavanna | first6 = L. | title = Solitary fibrous tumors of the pleura: a case report and review of the literature. | journal = Tumori | volume = 99 | issue = 4 | pages = e177-83 | month = | year = | doi = 10.1700/1361.15120 | PMID = 24326857 }}</ref> | ||
*Elderly. | *Elderly. | ||
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==Gross/radiology== | ==Gross/radiology== | ||
*Chest wall mass. | *Chest wall mass. | ||
**May be "large".<ref name=pmid17075563/> | |||
==Microscopic== | ==Microscopic== | ||
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www: | www: | ||
*[http://path.upmc.edu/cases/case216/dx.html SFT (upmc.edu)]. | *[http://path.upmc.edu/cases/case216/dx.html SFT (upmc.edu)]. | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698259/figure/f2/ Pleural SFT (nih.gov)].<ref name=pmid23825765/> | |||
==IHC== | ==IHC== | ||
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Others: | Others: | ||
*WT1 -ve (+ve in 1 of 10 cases<ref name=pmid18528287>{{Cite journal | last1 = Bing | first1 = Z. | last2 = Pasha | first2 = TL. | last3 = Acs | first3 = G. | last4 = Zhang | first4 = PJ. | title = Cytoplasmic overexpression of WT-1 in gastrointestinal stromal tumor and other soft tissue tumors. | journal = Appl Immunohistochem Mol Morphol | volume = 16 | issue = 4 | pages = 316-21 | month = Jul | year = 2008 | doi = 10.1097/PAI.0b013e31815c2e02 | PMID = 18528287 }}</ref>). | *WT1 -ve (+ve in 1 of 10 cases<ref name=pmid18528287>{{Cite journal | last1 = Bing | first1 = Z. | last2 = Pasha | first2 = TL. | last3 = Acs | first3 = G. | last4 = Zhang | first4 = PJ. | title = Cytoplasmic overexpression of WT-1 in gastrointestinal stromal tumor and other soft tissue tumors. | journal = Appl Immunohistochem Mol Morphol | volume = 16 | issue = 4 | pages = 316-21 | month = Jul | year = 2008 | doi = 10.1097/PAI.0b013e31815c2e02 | PMID = 18528287 }}</ref>). | ||
*Desmin -ve.<ref name=pmid23825765>{{Cite journal | last1 = Zhu | first1 = Y. | last2 = Du | first2 = K. | last3 = Ye | first3 = X. | last4 = Song | first4 = D. | last5 = Long | first5 = D. | title = Solitary fibrous tumors of pleura and lung: report of twelve cases. | journal = J Thorac Dis | volume = 5 | issue = 3 | pages = 310-3 | month = Jun | year = 2013 | doi = 10.3978/j.issn.2072-1439.2013.05.19 | PMID = 23825765 }}</ref> | |||
*CD117 -ve.<ref name=pmid23825765/> | |||
Suggested stains:{{fact}} | Suggested stains:{{fact}} | ||