Difference between revisions of "Glycogen-rich clear cell carcinoma of the breast"

From Libre Pathology
Jump to navigation Jump to search
(redirect)
 
(split out)
Line 1: Line 1:
#redirect [[Invasive_breast_cancer#Glycogen-rich_clear_cell_carcinoma_of_the_breast]]
'''Glycogen-rich_clear cell carcinoma of the breast''' is rare type of [[invasive breast cancer]].
 
It may be abbreviated '''GRCC'''.
 
==General==
*Very rare.
*Possibly a variant of [[apocrine carcinoma of the breast|apocrine carcinoma]].<ref name=pmid7611537>{{Cite journal  | last1 = Hayes | first1 = MM. | last2 = Seidman | first2 = JD. | last3 = Ashton | first3 = MA. | title = Glycogen-rich clear cell carcinoma of the breast. A clinicopathologic study of 21 cases. | journal = Am J Surg Pathol | volume = 19 | issue = 8 | pages = 904-11 | month = Aug | year = 1995 | doi =  | PMID = 7611537 }}
</ref>
*Prognosis usu. poor.
 
==Microscopic==
Features:
*Groups of cells with abundant clear cytoplasm - need to comprise 90% of the tumour.<ref name=pmid20551566>{{Cite journal  | last1 = Thondavadi | first1 = SR. | last2 = Krishnamurthy | first2 = J. | last3 = Gubbanna | first3 = VM. | title = A case report of glycogen-rich clear cell carcinoma of breast. | journal = Indian J Pathol Microbiol | volume = 53 | issue = 2 | pages = 374-5 | month =  | year =  | doi = 10.4103/0377-4929.64289 | PMID = 20551566 | URL = http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2010;volume=53;issue=2;spage=374;epage=375;aulast=Thondavadi }}</ref>
**Various architectural arrangements: cords, trabeculae, clusters, cribriform.
**Minimal nuclear pleomorphism.
 
Notes:
*Histologic appearance may be similar to ''[[hyalinizing clear cell carcinoma]]''.
 
DDx:
*[[Signet-ring carcinoma]].
*Lipid-rich carcinoma.
*[[Apocrine carcinoma of the breast|Apocrine carcinoma]].
*[[Secretory carcinoma of the breast|Secretory carcinoma]].
 
===Images===
www:
*[http://www.ijpmonline.org/viewimage.asp?img=IndianJPatholMicrobiol_2010_53_2_374_64289_f1.jpg GRCC (ijpmonline.org)].<ref name=pmid20551566/>
 
==Stains==
Features:<ref name=pmid20551566/>
*PAS +ve.
*PASD -ve.
 
Others:<ref name=pmid20551566/>
*Oil red O -ve.
**Lipid-rich carcinoma +ve.
 
==IHC==
Features:<ref name=pmid20551566/>
*[[BRST2]] -ve.
**Apocrine carcinoma +ve.
 
==See also==
*[[Invasive breast cancer]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Invasive breast cancer]]

Revision as of 11:20, 14 February 2014

Glycogen-rich_clear cell carcinoma of the breast is rare type of invasive breast cancer.

It may be abbreviated GRCC.

General

Microscopic

Features:

  • Groups of cells with abundant clear cytoplasm - need to comprise 90% of the tumour.[2]
    • Various architectural arrangements: cords, trabeculae, clusters, cribriform.
    • Minimal nuclear pleomorphism.

Notes:

DDx:

Images

www:

Stains

Features:[2]

  • PAS +ve.
  • PASD -ve.

Others:[2]

  • Oil red O -ve.
    • Lipid-rich carcinoma +ve.

IHC

Features:[2]

  • BRST2 -ve.
    • Apocrine carcinoma +ve.

See also

References

  1. ↑ Hayes, MM.; Seidman, JD.; Ashton, MA. (Aug 1995). "Glycogen-rich clear cell carcinoma of the breast. A clinicopathologic study of 21 cases.". Am J Surg Pathol 19 (8): 904-11. PMID 7611537.
  2. ↑ 2.0 2.1 2.2 2.3 2.4 Thondavadi, SR.; Krishnamurthy, J.; Gubbanna, VM.. "A case report of glycogen-rich clear cell carcinoma of breast.". Indian J Pathol Microbiol 53 (2): 374-5. doi:10.4103/0377-4929.64289. PMID 20551566.
Retrieved from "https://librepathology.org/w/index.php?title=Glycogen-rich_clear_cell_carcinoma_of_the_breast&oldid=29278"