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*Thought to result from alteration of dopamine receptor density. The D2 receptor in particular, which is thought to be important in temperature regulation, is decreased in psychotic cocaine abusers.<ref name=pmid8768172/> | *Thought to result from alteration of dopamine receptor density. The D2 receptor in particular, which is thought to be important in temperature regulation, is decreased in psychotic cocaine abusers.<ref name=pmid8768172/> | ||
==Toxicology== | ==Toxicology & biochemistry== | ||
===General=== | |||
Things usually collected at autopsy: | |||
#Blood in EDTA tube (genetic testing). | |||
#Urine toxicology. | |||
#*Useful to evaluate ''myoglobin''. | |||
#Vitreous (biochemistry). | |||
Myoglobin DDx: | |||
*Neuroleptic malignant syndrome. | |||
*Malignant hyperthermia. | |||
*Serotonin syndrome. | |||
===Ethanol=== | ===Ethanol=== | ||
*Usually measure in Canada: ''mass of EtOH (mg)/volume of blood (mL)''. | *Usually measure in Canada: ''mass of EtOH (mg)/volume of blood (mL)''. |
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