From Libre Pathology
(Redirected from Xanthelasma)
Jump to navigation Jump to search

The eyelid is occasionally sent to pathology. Information about the eye is found in the eye article.


Malignant tumours of the eyelid

Malignant eyelid tumour in order of frequency:[2]

Specific entities


  • Xanthelasma palpebrarum redirects here.


  • ~8% of eyelid tumours in one series.[1]
  • Type of xanthoma.[3]
    • It is said that a xanthoma can be anywhere. If it is on the eyelid it is a xanthelasma; a xanthelasma is a xanthoma of the eyelid.[4]
  • Associated with increased serum lipid levels.[5]
    • Incidence of elevated cholesterol is higher in younger patients.[6]


  • Exophytic lesion (on eyelid or around it) - classically yellow.




  • Collection of foamy histiocytes within the dermis.


Sign out

Eyelid, Lesion Right Upper Lid, Excision:
- Benign skin tag with rare foamy histiocytes in keeping with an early xanthelasma.
- NEGATIVE for malignancy.

Xanthelasma may be associated with metabolic abnormalities. A lipid profile is suggested if not done recently.  


See also


  1. 1.0 1.1 Gundogan, FC.; Yolcu, U.; Tas, A.; Sahin, OF.; Uzun, S.; Cermik, H.; Ozaydin, S.; Ilhan, A. et al. (2015). "Eyelid tumors: clinical data from an eye center in Ankara, Turkey.". Asian Pac J Cancer Prev 16 (10): 4265-9. PMID 26028084.
  2. Margo CE, Mulla ZD (February 1998). "Malignant tumors of the eyelid: a population-based study of non-basal cell and non-squamous cell malignant neoplasms". Arch Ophthalmol 116 (2): 195–8. doi:10.1001/archopht.116.2.195. PMID 9488271.
  3. Pathania, V.; Chatterjee, M.. "Ultrapulse carbon dioxide laser ablation of xanthelasma palpebrarum: a case series.". J Cutan Aesthet Surg 8 (1): 46-9. doi:10.4103/0974-2077.155084. PMID 25949023.
  4. URL: https://www.merriam-webster.com/medical/xanthelasma. Accessed on: May 1, 2023.
  5. Rubinstein, TJ.; Mehta, MP.; Schoenfield, L.; Perry, JD.. "Orbital xanthogranuloma in an adult patient with xanthelasma palpebrarum and hypercholesterolemia.". Ophthal Plast Reconstr Surg 30 (1): e6-8. doi:10.1097/IOP.0b013e3182873d13. PMID 23503059.
  6. Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 628. ISBN 978-0443066542.