Wound healing

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Wound healing is important in surgery and occasions discussed in pathology. It depends on local factors and systemic factors.

Local factors

These include:[1][2]

  • Size of wound.
  • Vascularization.
  • Presence of infection.
  • Etiology of wound.
  • Presence of foreign bodies.
  • Wound motion/tension.
  • Presence of neoplasm.[3]

Systemic factors

These include:[1]

  • Nutritional status.
  • Cardiovascular disease.
  • Endocrine conditions - diabetes mellitus, excessive steroids.
  • Systemic diseases - Ehlers-Danlos syndrome.
  • Systemic infection.

See also


  1. 1.0 1.1 Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 64. ISBN 978-1416054542.
  2. Rodriguez-Merchan, EC. (Feb 2012). "Surgical wound healing in bleeding disorders.". Haemophilia. doi:10.1111/j.1365-2516.2012.02760.x. PMID 22335628.
  3. Hachenberg, T.; Sentürk, M.; Jannasch, O.; Lippert, H. (Sep 2010). "[Postoperative wound infections. Pathophysiology, risk factors and preventive concepts].". Anaesthesist 59 (9): 851-66; quiz 867-8. doi:10.1007/s00101-010-1789-4. PMID 20830460.