Uterine tumour resembling an ovarian sex cord stromal tumour
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Uterine tumour resembling an ovarian sex cord stromal tumour, abbreviated UTROSCT, is a very rare uterine tumour.
General
- Super rare.[1]
- Typically postmenopausal - mean age ~ 52 years.[1]
- Usually presentation is abnormal uterine bleeding.[1]
- Prognosis good if tumour predominantly sex cord-like, i.e. Type 2.[1]
Microscopic
Features:
- Look like sex cord tumour:[2]
- May have: anastomosing cords, trabeculae, small nests and/or tubules.
Notes:
- May be subdivided into:[3]
- Type 1 <50% sex cord-component (may be referred to as endometrial stromal tumour with sex cord-like elements[1]).
- Type 2 >50% sex cord-component.
DDx:
Images
IHC
Features:[3]
- Calretinin +ve (sex cord-like component).
- CD10 +ve (stroma).
- PR +ve.
- Inhibin +ve/-ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Blake, EA.; Sheridan, TB.; Wang, KL.; Takiuchi, T.; Kodama, M.; Sawada, K.; Matsuo, K. (Oct 2014). "Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature.". Eur J Obstet Gynecol Reprod Biol 181: 163-70. doi:10.1016/j.ejogrb.2014.07.050. PMID 25150955.
- ↑ Irving, JA.; Carinelli, S.; Prat, J. (Jan 2006). "Uterine tumors resembling ovarian sex cord tumors are polyphenotypic neoplasms with true sex cord differentiation.". Mod Pathol 19 (1): 17-24. doi:10.1038/modpathol.3800475. PMID 16118629.
- ↑ 3.0 3.1 Bakula-Zalewska, E.; Danska-Bidzinska, A.; Kowalewska, M.; Piascik, A.; Nasierowska-Guttmejer, A.; Bidzinski, M. (Dec 2014). "Uterine tumors resembling ovarian sex cord tumors, a clinicopathologic study of six cases.". Ann Diagn Pathol 18 (6): 329-32. doi:10.1016/j.anndiagpath.2014.08.009. PMID 25257516.
- ↑ Baker, P.; Oliva, E. (Mar 2007). "Endometrial stromal tumours of the uterus: a practical approach using conventional morphology and ancillary techniques.". J Clin Pathol 60 (3): 235-43. doi:10.1136/jcp.2005.031203. PMID 17347285.
- ↑ Hashmi, AA.; Faridi, N.; Edhi, MM.; Khan, M. (2014). "Uterine tumor resembling ovarian sex cord tumor (UTROSCT), case report with literature review.". Int Arch Med 7 (1): 47. doi:10.1186/1755-7682-7-47. PMID 25395990.