Tularemia

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Tularemia is an infectious disease that cause lymphadenopathy.

General

  • Caused by Francisella tularensis, a Gram-negative coccobacillus.[1]
  • Rare.

Treatment:

  • Antibiotics.

Gross

Microscopic

Features:

  • Necrotizing granulomas with:
    • Neutrophils present in microabscess (necrotic debris) - key feature.
      • Microabscesses often described as "stellate" (star-shaped).
  • Microorganisms consistent with F. tularensis.

DDx of stellate abscess in lymph nodes - cat split:[3]

See also

References

  1. Dentan, C.; Pavese, P.; Pelloux, I.; Boisset, S.; Brion, JP.; Stahl, JP.; Maurin, M. (Jun 2013). "Treatment of tularemia in pregnant woman, France.". Emerg Infect Dis 19 (6): 996-8. doi:10.3201/eid1906.130138. PMID 23735285.
  2. Asano, S. (2012). "Granulomatous lymphadenitis.". J Clin Exp Hematop 52 (1): 1-16. PMID 22706525.
  3. URL: http://www.dermpathmd.com/mnemonics/mnemonics_dermatopathology.htm. Accessed on: 23 September 2011.