Traumatic neuroma

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Traumatic neuroma is a common hand and foot ditzel and grouped with the peripheral nerve sheath tumours.

These may simply be referred to as neuroma, a rather non-specific term that may be used to describe a number of different things.

General

  • Consequence of trauma - diagnosis requires history of trauma.
    • May mimic a cancer recurrence at the site of a surgery.[1]

Microscopic

Features:[2][1]

  • +/-Nerve - that was injured.
  • Grouping of disordered nerve fibre bundles in fibrous tissue (collagen) - key feature.
  • +/-Myxoid change.
  • +/-Axonal swellings (ovoid pink/purple blobs).

DDx:

Images

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Submitted as "Neuroma Left Foot", Excision:
	- Consistent with neuroma.
	- Atherosclerosis, moderate.

Block letters

SOFT TISSUE LESION, RIGHT WRIST, EXCISION:
- TRAUMATIC NEUROMA.
- BENIGN FIBROADIPOSE TISSUE.

Micro

The sections show disordered nerve fibre bundles in fibrous tissue.

See also

References

  1. 1.0 1.1 1.2 Li, Q.; Gao, EL.; Yang, YL.; Hu, HY.; Hu, XQ. (2012). "Traumatic neuroma in a patient with breast cancer after mastectomy: a case report and review of the literature.". World J Surg Oncol 10: 35. doi:10.1186/1477-7819-10-35. PMID 22330690.
  2. Tadrous, Paul.J. Diagnostic Criteria Handbook in Histopathology: A Surgical Pathology Vade Mecum (1st ed.). Wiley. pp. 317. ISBN 978-0470519035.
  3. Kwon, JH.; Ryu, SW.; Kang, YN.. "Traumatic neuroma around the celiac trunk after gastrectomy mimicking a nodal metastasis: a case report.". Korean J Radiol 8 (3): 242-5. PMC 2627419. PMID 17554193. //www.ncbi.nlm.nih.gov/pmc/articles/PMC2627419/.
  4. Kitcat, M.; Hunter, JE.; Malata, CM. (2009). "Sciatic neuroma presenting forty years after above-knee amputation.". Open Orthop J 3: 125-7. doi:10.2174/1874325000903010125. PMID 20224738.