Tissue descriptors

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Tissue descriptors, also tissue characteristics, are things to think about when describing tissue to someone else.

Architecture/arrangement

  • Gland forming.
  • Palisading.
  • Rosettes.
  • Sheets.
  • Nests.
  • Cords.
  • Epithelial specific.
    • Stratified.
    • Pseudostratified.

Borders of the cell

  • Distinct.
  • Indistinct.
  • Spacing between cells (e.g. intercellular bridges).

Cytology

  • Size - relative to RBC.
  • Morphology.
    • Epithelioid.
    • Spindle.
    • Columnar.
    • Cuboidal.
  • Nucleus.
    • Shape.
    • Stratification.
      • Basal.
      • Peripheral.
      • Central.
    • Multinucleation.
    • Nucleoli.
      • Number.
      • Size.
    • Chromatin.
      • Inclusions.
      • Consistency.
        • Bland.
        • Clearing.
        • Stippled (salt 'n pepper).
  • Cytoplasm.
    • Colour.
    • Consistency.
    • Inclusions.

Other

  • Vessels.
  • Necrosis.
  • Hemorrhage.
  • Mitoses.
    • Atypical mitoses.
  • Inflammatory cells.

Simplified classification

  • Arrangement - sheets, glands, nests, mixed population.
    • Morphology - spindle, epithelioid, polygonal.
  • Borders - distinct, indistinct, spaces.
  • Cytoplasm - colour, other.
  • DNA (nucleus) - number, location, size, nucleoli.

Sign out

Architecture: sheeting, trabecular, no glandular formations.

Cellularity (cellular density): high.

Cell morphology
-Shape: epithelioid.
-Cell size: intermediate (~16 micrometers).
-Cell size variation: mild.
-Cell borders: not distinct.

Cytoplasm:
-Quantity: moderate.
-Colour (H&E): light, grey.
-Perinuclear changes: clearing.

Nucleus:
-Number: singular.
-Chromatin: coarse.
-Nucleolus: singular, irregular.
-Inclusions: none.
-Grooves: none

Necrosis: focal.
Mitoses: 32/2.376 mm^2.

See also