Talk:Lung cancer staging

Multifocal adenocarcinoma

A separate focus of adenocarcinoma is seen. A synchronous primary cannot be entirely excluded; however, this is presumed to be an intrapulmonary metastasis, as it has a non-lepidic morphology. The case is staged as pT3 on account of the separate focus.

General Comment - Cancer Staging:
The morphological similarity and immunostaining would be in keeping with a primary tumour and a metastasis; the case was staged under this presumption.

The biomarker findings will provide additional information in the determination: two concurrent primaries VERSUS primary with metastasis.  
CLINICAL AND MOLECULAR CORRELATION IS REQUIRED for the staging of this case.