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Difference between revisions of "Vulva and vagina"
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==Classic VIN== | ==Classic VIN== | ||
=== | ===Epidemiology=== | ||
*Classic VIN, like CIN, is associated with [[HPV]] and seen in younger women. | *Classic VIN, like CIN, is associated with [[HPV]] and seen in younger women. | ||
===General=== | ===General=== | ||
* | *Classic VIN is graded like cervical pre-cancerous lesions: | ||
**VIN I | **VIN I. | ||
*** | ***Not common. | ||
**VIN II | **VIN II. | ||
*** | ***Not common. | ||
**VIN III | **VIN III. | ||
*** | ***Commonly seen. | ||
DDx: | DDx: | ||
*Condyloma (genital wart) | *Condyloma (genital wart). | ||
**Most caused by HPV. | **Most caused by HPV. | ||
===Micro. of classic VIN=== | ===Micro. of classic VIN=== | ||
*Increased NC ratio. | *Increased NC ratio. | ||
*Multinucleation. | *Multinucleation. | ||
*Lack of maturation to surface (not very useful -- unlike in the cervix).<ref>LAE | *Lack of maturation to surface (not very useful -- unlike in the cervix).<ref>LAE. February 2009.</ref> | ||
*Apical mitoses. | *Apical mitoses. | ||