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Difference between revisions of "Thyroid gland"
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→Hürthle cell neoplasm: more
(→Hürthle cell neoplasm: more) |
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*NSE +ve. | *NSE +ve. | ||
==Hürthle cell | ==Hürthle cell neoplasms== | ||
*[[AKA]] oncocytic neoplasm. | *[[AKA]] oncocytic neoplasm. | ||
===General=== | |||
*Hürthle cell adenoma. | *Incidence: uncommon. | ||
*Hürthle cell carcinoma. | *This is a general category - includes: | ||
**Hürthle cell adenoma. | |||
**Hürthle cell carcinoma. | |||
*Some advocate ''total thyroidectomy'' for all Hürthle cell neoplasms - as it is difficult to reliably differentiate adenomas and carcinomas.<ref name=pmid9697901>{{Cite journal | last1 = Wasvary | first1 = H. | last2 = Czako | first2 = P. | last3 = Poulik | first3 = J. | last4 = Lucas | first4 = R. | title = Unilateral lobectomy for Hurthle cell adenoma. | journal = Am Surg | volume = 64 | issue = 8 | pages = 729-32; discussion 732-3 | month = Aug | year = 1998 | doi = | PMID = 9697901 }}</ref> | |||
* | |||
====Adenoma vs. carcinoma==== | |||
</ref> | Suggestive for carcinoma:<ref name=pmid9697901/> | ||
*Male. | |||
*>4 cm | |||
**Adenomas usu. <3 cm. | |||
Definite for carcinoma:<ref name=pmid9697901/> | |||
*Lymphovascular invasion. | |||
*Capsular invasion. | |||
===Gross=== | ===Gross=== | ||
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Negatives: | Negatives: | ||
*Lack nuclear features of papillary thyroid carcinoma. | *Lack nuclear features of [[papillary thyroid carcinoma]]. | ||
*Lack features of medullary thyroid carcinoma. | *Lack features of [[medullary thyroid carcinoma]]. | ||
DDx:<ref name=pmid18684023>{{cite journal |author=Montone KT, Baloch ZW, LiVolsi VA |title=The thyroid Hürthle (oncocytic) cell and its associated pathologic conditions: a surgical pathology and cytopathology review |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=8 |pages=1241–50 |year=2008 |month=August |pmid=18684023 |doi= |url=}}</ref> | DDx:<ref name=pmid18684023>{{cite journal |author=Montone KT, Baloch ZW, LiVolsi VA |title=The thyroid Hürthle (oncocytic) cell and its associated pathologic conditions: a surgical pathology and cytopathology review |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=8 |pages=1241–50 |year=2008 |month=August |pmid=18684023 |doi= |url=}}</ref> | ||