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Difference between revisions of "Vascular tumours"
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→Kaposiform hemangioendothelioma: more
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*Childhood tumour.<ref name=pmid15105642>{{Cite journal | last1 = Lyons | first1 = LL. | last2 = North | first2 = PE. | last3 = Mac-Moune Lai | first3 = F. | last4 = Stoler | first4 = MH. | last5 = Folpe | first5 = AL. | last6 = Weiss | first6 = SW. | title = Kaposiform hemangioendothelioma: a study of 33 cases emphasizing its pathologic, immunophenotypic, and biologic uniqueness from juvenile hemangioma. | journal = Am J Surg Pathol | volume = 28 | issue = 5 | pages = 559-68 | month = May | year = 2004 | doi = | PMID = 15105642 }}</ref> | *Childhood tumour.<ref name=pmid15105642>{{Cite journal | last1 = Lyons | first1 = LL. | last2 = North | first2 = PE. | last3 = Mac-Moune Lai | first3 = F. | last4 = Stoler | first4 = MH. | last5 = Folpe | first5 = AL. | last6 = Weiss | first6 = SW. | title = Kaposiform hemangioendothelioma: a study of 33 cases emphasizing its pathologic, immunophenotypic, and biologic uniqueness from juvenile hemangioma. | journal = Am J Surg Pathol | volume = 28 | issue = 5 | pages = 559-68 | month = May | year = 2004 | doi = | PMID = 15105642 }}</ref> | ||
*Approximately half have ''Kasabach–Merritt phenomenon'' = vascular tumour --> coagulopathy. | *Approximately half have ''Kasabach–Merritt phenomenon'' = vascular tumour --> coagulopathy. | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=pmid1706068/> | ||
* | *Spindle cells lesions in sheets or nodules. | ||
*+/-Round tumour nodules - "cannon ball" appearance. | |||
DDx: | |||
*[[Kaposi sarcoma]].<ref name=pmid1706068>{{Cite journal | last1 = Miller | first1 = K. | title = Sister-chromatid exchange in human B- and T-lymphocytes exposed to bleomycin, cyclophosphamide, and ethyl methanesulfonate. | journal = Mutat Res | volume = 247 | issue = 1 | pages = 175-82 | month = Mar | year = 1991 | doi = | PMID = 1706068 | url = http://www.nature.com/modpathol/journal/v14/n11/full/3880441a.html }}</ref> | |||
===IHC=== | ===IHC=== | ||
Features:<ref name=pmid1706068/> | |||
*Vimentin +ve. | |||
*C31 +ve. | |||
*CD34 +ve. | |||
*UEA-1 lectin +ve. | |||
==Epithelioid hemangioendothelioma== | ==Epithelioid hemangioendothelioma== | ||