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Difference between revisions of "Kidney tumours"
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→Renal tumour with Xp11.2 translocation: tweak gr.
(→Microscopic: +iamges) |
m (→Renal tumour with Xp11.2 translocation: tweak gr.) |
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==Renal tumour with Xp11.2 translocation== | ==Renal tumour with Xp11.2 translocation== | ||
===General=== | ===General=== | ||
*Defined by the presence of a fusion gene | *Defined by the presence of a fusion gene formed with TFE3 @ Xp11.2. | ||
*TFE3 is the gene involved in the translocation seen in [[alveolar soft part sarcoma]] (ASPS). | *TFE3 is the gene involved in the translocation seen in [[alveolar soft part sarcoma]] (ASPS). | ||
*Poor prognosis ~ 50% present at stage IV, majority of lymph node metastases. | *Poor prognosis ~ 50% present at stage IV, majority of lymph node metastases. | ||