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(→Arteriolar hyalinosis: more) |
(→Arteriolar hyalinosis: more) |
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Line 231: | Line 231: | ||
*[[Hypertension]]. | *[[Hypertension]]. | ||
*Aging. | *Aging. | ||
*Drugs - tacrolimus, cyclosporine. | *Drugs - calcineurin inhibitors (tacrolimus, cyclosporine). | ||
Note: | Note: | ||
*Arteriolar hyalinosis - involves ''afferent'' and ''efferent'' arterioles in diabetes, in others it is only the afferent. | *Arteriolar hyalinosis - involves ''afferent'' and ''efferent'' arterioles in diabetes, in others it is only the afferent. | ||
===Atherosclerosis=== | |||
{{Main|Atherosclerosis}} | |||
Microscopic: | |||
*Intimal thickening of medium-sized vessels. | |||
**Where is the intima/media interface? | |||
***Internal elastic lamina - wavy band of eosinophilic stain material on H&E. | |||
Grading - based on the thickness of the media and intima: | |||
*Mild: (tunica) media > (tunica) intima. | |||
*Moderate: media = intima. | |||
*Severe: media < intima. | |||
===Mesangial hypercellularity=== | ===Mesangial hypercellularity=== |
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