Difference between revisions of "Gestational trophoblastic disease"

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==Choriocarcinoma==
==Choriocarcinoma==
===General===
*Classified as a [[germ cell tumour]].
*Classified as a [[germ cell tumour]].
*Usually a mixed tumour, i.e. pure choriocarcinoma is rare, e.g. [[dysgerminoma]] + choriocarcinoma.
*Usually a mixed tumour, i.e. pure choriocarcinoma is rare, e.g. [[dysgerminoma]] + choriocarcinoma.
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*More common at extremes of fertile age (teens and 40-50 years).
*More common at extremes of fertile age (teens and 40-50 years).


===Micro===
===Microscopic===
Features:
*[[Nuclear pleomorphism]] - usually marked.
*[[Nuclear pleomorphism]] - usually marked.
*Often haemorrhage.
*Often haemorrhage.
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*[http://www.webpathology.com/image.asp?case=36&n=1 Choriocarcinoma (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=36&n=1 Choriocarcinoma (webpathology.com)].
*[http://oac.med.jhmi.edu/Pathology/Repro/Placenta/279B_Full.html Choriocarcinoma - testicular (med.jhmi.edu)].
*[http://oac.med.jhmi.edu/Pathology/Repro/Placenta/279B_Full.html Choriocarcinoma - testicular (med.jhmi.edu)].


Notes:
Notes:
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