Difference between revisions of "Medical kidney diseases"

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Line 265: Line 265:
| '''Image'''
| '''Image'''
|-
|-
|Nodular GS
|[[Nodular glomerulosclerosis]]
| nodular mesangial matrix expansion
| nodular mesangial matrix expansion
| GBM thickening, both afferent and efferent arteriole hyalinzed
| GBM thickening, both afferent and efferent arteriole hyalinized
| EM?
| EM?
| presentation?
| presentation?
| diabetes mellitus
| [[diabetes mellitus]]
| membranous nephropathy (?)
| [[amyloidosis]]
| Image?
| Image?
|-
|-
|Focal segmental GS (FSGS)
|[[Focal segmental glomerulosclerosis]] (FSGS)
| focal sclerosis of glom
| focal sclerosis of gloms
| +/-interstitial fibrosis
| +/-interstitial fibrosis
| EM?
| EM?
| nephrotic syndrome
| nephrotic syndrome
| primary FSGS, secondary FSGS; unresponsive to steroids, worse prognosis than MCD
| primary FSGS, secondary FSGS ([[HIV]], [[IVDU]], obesity, [[parvovirus B19]], [[Alport syndrome]]); unresponsive to steroids, worse prognosis than MCD
| Pathol. DDx?
| Pathol. DDx?
| Image?
| Image?
Line 288: Line 288:
| EM?
| EM?
| nephrotic syndrome
| nephrotic syndrome
| hep B, hep C, carcinoma, NSAID toxicity, SLE, idiopathic
| [[hepatitis B]], [[hepatitis C]], carcinoma, NSAID toxicity, SLE, idiopathic
| Nodular GS (?)
| Nodular GS (?)
| Image?
| Image?
Line 297: Line 297:
| EM changes
| EM changes
| nephrotic syndrome
| nephrotic syndrome
| idiopathic vs. secondary; idiopathic responds to steroids
| primary vs. secondary ([[lymphoproliferative disorder]], NSAIDs); idiopathic responds to steroids
| Pathol. DDx?
| Pathol. DDx?
| Image?
| Image?
Line 306: Line 306:
| IgA +ve
| IgA +ve
| mixed nephrotic/nephritic
| mixed nephrotic/nephritic
| Clinical?
| primary vs. secondary (Henoch-Schoenlein purpura)
| Pathol. DDx?
| Pathol. DDx?
| Image?  
| Image?  
Line 315: Line 315:
| subepithelial deposits
| subepithelial deposits
| mixed nephrotic/nephritic
| mixed nephrotic/nephritic
| Clinical?
| SLE, cryoglobulinemia, [[hepatitis B]], [[hepatitis C]]
| Pathol. DDx?
| Pathol. DDx?
| Image?  
| Image?  
Line 329: Line 329:
|-
|-
|Rapidly progressive GN (RPGN)
|Rapidly progressive GN (RPGN)
| cresents
| crescents
| Other findings?
| Other findings?
| EM?
| EM?
| nephritic syndrome
| nephritic syndrome
| Clinical?
| AGBM, ANCA-vasculitis
| Pathol. DDx?
| Pathol. DDx?
| Image?  
| Image?  
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