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Difference between revisions of "Testis"
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→Diagnoses (overview): more
(→Intratubular germ cell neoplasia: +abbrev.) |
(→Diagnoses (overview): more) |
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!| Image | !| Image | ||
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| Intratubular germ cell neoplasia (ITGCN) | | [[Intratubular germ cell neoplasia]] (ITGCN) | ||
| nests of small fried egg cells | | nests of small fried egg cells | ||
| large central nucleus, clear <br>cytoplasm, squared-off nuclear membrane, [[nucleoli]]<ref name=Ref_GUP538>{{Ref GUP|538}}</ref> | | large central nucleus, clear <br>cytoplasm, squared-off nuclear membrane, [[nucleoli]]<ref name=Ref_GUP538>{{Ref GUP|538}}</ref> | ||
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| [http://commons.wikimedia.org/wiki/File:Intratubular_germ_cell_neoplasia_high_mag.jpg], [http://commons.wikimedia.org/wiki/File:Intratubular_germ_cell_neoplasia_high_mag_cropped.jpg] | | [http://commons.wikimedia.org/wiki/File:Intratubular_germ_cell_neoplasia_high_mag.jpg], [http://commons.wikimedia.org/wiki/File:Intratubular_germ_cell_neoplasia_high_mag_cropped.jpg] | ||
|- | |- | ||
| Seminoma | | [[Seminoma]] | ||
| fried egg cells | | fried egg cells | ||
| fried egg-like cells (central nucleus, clear <br>cytoplasm) with squared-off nuclear <br>membrane, nucleoli, lymphocytic infiltrate, granulomata,<br>syncytiotrophoblastic giant cells<ref name=Ref_GUP542>{{Ref GUP|542}}</ref> | | fried egg-like cells (central nucleus, clear <br>cytoplasm) with squared-off nuclear <br>membrane, nucleoli, lymphocytic infiltrate, granulomata,<br>syncytiotrophoblastic giant cells<ref name=Ref_GUP542>{{Ref GUP|542}}</ref> | ||
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| [http://commons.wikimedia.org/wiki/File:Primitive_neuroepithelium_intermed_mag.jpg] | | [http://commons.wikimedia.org/wiki/File:Primitive_neuroepithelium_intermed_mag.jpg] | ||
|- | |- | ||
| Spermatocytic seminoma | | [[Spermatocytic seminoma]] | ||
| population of 3 cells | | population of 3 cells | ||
| pop.: (1) small cell with high NC ratio (mature lymphocyte-like), (2) medium with nucleoli, (3) large cells with filamentous chromatin - few present | | pop.: (1) small cell with high NC ratio (mature lymphocyte-like), (2) medium with nucleoli, (3) large cells with filamentous chromatin - few present | ||
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| [http://commons.wikimedia.org/wiki/File:Spermatocytic_seminoma_high_mag.jpg] | | [http://commons.wikimedia.org/wiki/File:Spermatocytic_seminoma_high_mag.jpg] | ||
|- | |- | ||
| Mixed germ cell tumour | | [[Mixed germ cell tumour]] | ||
| NA | | NA | ||
| common combinations: teratoma + embryonal carcinoma + endodermal sinus tumour (yolk sac tumour) (TEE); seminoma + embryonal (SE); embryonal + teratoma (TE) | | common combinations: teratoma + embryonal carcinoma + endodermal sinus tumour (yolk sac tumour) (TEE); seminoma + embryonal (SE); embryonal + teratoma (TE) | ||
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!| Image | !| Image | ||
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| Leydig cell tumour | | [[Leydig cell tumour]] | ||
| intersitial cell cluster with eosinophilic cytoplasm | | intersitial cell cluster with eosinophilic cytoplasm | ||
| cytoplasmic vacuolization, uniform nuclei with nucleoli | | cytoplasmic vacuolization, uniform nuclei with nucleoli | ||
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| [http://commons.wikimedia.org/wiki/File:Leydig_cell_tumour2.jpg] | | [http://commons.wikimedia.org/wiki/File:Leydig_cell_tumour2.jpg] | ||
|- | |- | ||
| Sertoli cell tumour | | [[Sertoli cell tumour]] | ||
| cells in cords or [[trabeculae]] | | cells in cords or [[trabeculae]] | ||
| light staining bubbly cytoplasm +/- large cytoplasmic vacuoles, granular chromatin | | light staining bubbly cytoplasm +/- large cytoplasmic vacuoles, granular chromatin | ||