Difference between revisions of "Prostate gland"

Prostate gland (view source)

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 ====Extraprostatic extension (EPE)====
-*Prostatectomy specimens: EPE is present if there is a "significant bulge" in the contour of the prostate at low power.
+*Prostatectomy specimens: EPE is present if there is either:
+*#A "significant bulge" in the contour of the prostate at low power ''and'' no fibromuscular tissue surrounding the malignant cells.
+*#Malignant cells directly adjacent to peri-prostatic adipose tissue.
 *Prostate biopsy: EPE is present if tumour touches adipose tissue.<ref name=pmid17707261>{{Cite journal  | last1 = Epstein | first1 = JI. | last2 = Srigley | first2 = J. | last3 = Grignon | first3 = D. | last4 = Humphrey | first4 = P. | title = Recommendations for the reporting of prostate carcinoma. | journal = Hum Pathol | volume = 38 | issue = 9 | pages = 1305-9 | month = Sep | year = 2007 | doi = 10.1016/j.humpath.2007.05.015 | PMID = 17707261 }}
 </ref>
-**The prostate, at the apex, may have some skeletal muscle -- it is hard to define the extent... ergo no EPE at apex. (????)
+**The prostate, at the apex, may have some skeletal muscle. Thus, it is difficult to define extention... ergo EPE not called at the apex.
 ===Reporting prostate cancer===