Difference between revisions of "Prostate gland"

Prostate gland (view source)

956 bytes added , 15:16, 18 October 2011

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 ===IHC===
-*AMACR +ve, p63 -ve, HMWCK (34betaE12) -ve .
+*AMACR +ve.
-*Usually positive: PSA, PSAP.
+*AR +ve -- in prostate confined cancer.
+**Usu. -ve in LN +ve disease.<ref name=pmid20878946>{{Cite journal  | last1 = Fleischmann | first1 = A. | last2 = Rocha | first2 = C. | last3 = Schobinger | first3 = S. | last4 = Seiler | first4 = R. | last5 = Wiese | first5 = B. | last6 = Thalmann | first6 = GN. | title = Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases. | journal = Prostate | volume = 71 | issue = 5 | pages = 453-60 | month = Apr | year = 2011 | doi = 10.1002/pros.21259 | PMID = 20878946 }}</ref> *PSA +ve.
+*PSAP +ve.
+*p63 -ve.
+*HMWCK (34betaE12) -ve.
+Combination immunostains:
+*CAP (AMACR + HWCK).
+**Why '''CAP'''?
+***A. '''CA'''ncer of the '''P'''rostate.
+**[[AKA]] ''PIN''.<ref>URL: [http://www.antibodies-online.com/antibody/308235/anti-PIN-4+p63+Cytokeratin+HMW+p504S++AMACR/ http://www.antibodies-online.com/antibody/308235/anti-PIN-4+p63+Cytokeratin+HMW+p504S++AMACR/]. Accessed on: 18 October 2011.</ref>
 ===Mimics===