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Difference between revisions of "Prostate gland"
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→IHC: more
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===IHC=== | ===IHC=== | ||
*AMACR +ve | *AMACR +ve. | ||
* | *AR +ve -- in prostate confined cancer. | ||
**Usu. -ve in LN +ve disease.<ref name=pmid20878946>{{Cite journal | last1 = Fleischmann | first1 = A. | last2 = Rocha | first2 = C. | last3 = Schobinger | first3 = S. | last4 = Seiler | first4 = R. | last5 = Wiese | first5 = B. | last6 = Thalmann | first6 = GN. | title = Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases. | journal = Prostate | volume = 71 | issue = 5 | pages = 453-60 | month = Apr | year = 2011 | doi = 10.1002/pros.21259 | PMID = 20878946 }}</ref> *PSA +ve. | |||
*PSAP +ve. | |||
*p63 -ve. | |||
*HMWCK (34betaE12) -ve. | |||
Combination immunostains: | |||
*CAP (AMACR + HWCK). | |||
**Why '''CAP'''? | |||
***A. '''CA'''ncer of the '''P'''rostate. | |||
**[[AKA]] ''PIN''.<ref>URL: [http://www.antibodies-online.com/antibody/308235/anti-PIN-4+p63+Cytokeratin+HMW+p504S++AMACR/ http://www.antibodies-online.com/antibody/308235/anti-PIN-4+p63+Cytokeratin+HMW+p504S++AMACR/]. Accessed on: 18 October 2011.</ref> | |||
===Mimics=== | ===Mimics=== | ||