Difference between revisions of "Testis"

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replace GUP refs
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| Intratubular germ cell neoplasia (ITGCN)
| Intratubular germ cell neoplasia (ITGCN)
| nests of small fried egg cells
| nests of small fried egg cells
| large central nucleus, clear <br>cytoplasm, squared-off nuclear membrane, nucleoli<ref>GUP P.538.</ref>
| large central nucleus, clear <br>cytoplasm, squared-off nuclear membrane, nucleoli<ref name=Ref_GUP538>{{Ref GUP|538}}</ref>
| CD117
| CD117
| appearance similar to seminoma
| appearance similar to seminoma
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| Seminoma
| Seminoma
| fried egg cells
| fried egg cells
| fried egg-like cells (central nucleus, clear <br>cytoplasm) with squared-off nuclear <br>membrane, nucleoli, lymphocytic infiltrate, granulomata,<br>syncytiotrophoblastic giant cells<ref>GUP P.542.</ref>
| fried egg-like cells (central nucleus, clear <br>cytoplasm) with squared-off nuclear <br>membrane, nucleoli, lymphocytic infiltrate, granulomata,<br>syncytiotrophoblastic giant cells<ref name=Ref_GUP542>{{Ref GUP|542}}</ref>
| D2-40
| D2-40
| Dysgerminoma
| Dysgerminoma
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***Nucleus has "corners", i.e. it is ''not'' round.
***Nucleus has "corners", i.e. it is ''not'' round.
*Lymphoctyes common, not essential.
*Lymphoctyes common, not essential.
*May see [[syncytiotrophoblast]]s, AKA ''syncytiotrophoblastic giant cells'' (STGCs).<ref>GUP P.542.</ref>
*May see [[syncytiotrophoblast]]s, AKA ''syncytiotrophoblastic giant cells'' (STGCs).<ref name=Ref_GUP542>{{Ref GUP|542}}</ref>
**Large + irregular, vesicular nuclei.  
**Large + irregular, vesicular nuclei.  
**Eosinophilic vacuolated cytoplasm (contains hCG).
**Eosinophilic vacuolated cytoplasm (contains hCG).
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===Microscopy===
===Microscopy===
Features:<ref>GUP P.549</ref>
Features:<ref name=Ref_GUP549>{{Ref GUP|549}}</ref>
*Indistinct cell borders
*Indistinct cell borders
*Mitoses - common.
*Mitoses - common.
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===Microscopic===
===Microscopic===
Features:<ref>GUP P.581.</ref>
Features:<ref name=Ref_GUP581>{{Ref GUP|581}}</ref>
*Vacuolization - ''key feature''.
*Vacuolization - ''key feature''.
*Cytoplasm - clear to eosinophilic.
*Cytoplasm - clear to eosinophilic.
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