Difference between revisions of "Meningioma"

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349 bytes added ,  14:32, 12 October 2011
→‎Grade I: subdivide
(→‎Grade I: subdivide)
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====Grade I====
====Grade I====
*Meningothelial.
=====Meningothelial=====
**Most common.
*Most common.
**Microscopic: syncytial, nuclear clearing (pseudoinclusions).
 
*Fibrous (fibroblastic).
Microscopic:  
**Not collagen but looks like it. (It is really laminin or fibronectin).
*Syncytial, nuclear clearing ([[pseudoinclusions]]).
*Transistional.
 
**Rare.
=====Fibrous=====
*Psammomatous.
*AKA fibroblastic.
**Microscopic: [[Psammoma bodies]].
*Not collagen but looks like it. (It is really laminin or fibronectin).
*Angiomatous (vascular).
 
**May bleed like stink.
=====Transistional=====
*Microcystic.
*Rare.
**Microscopic: cystic appearance.
 
*Secretory.
=====Psammomatous=====
**Microscopic: intracytoplasmic inclusions that are CEA +ve and PAS +ve.
Microscopic:  
**Assoc. with brain edema; may have a worse outcome.
*[[Psammoma bodies]].
*Lymphoplasmacyte-rich.
 
*Metaplastic.
=====Angiomatous=====
**Much talked about... but very rare.
*AKA vascular.
**Microscopic: cartilage or bone formation.
*May bleed like stink.
 
=====Microcystic=====
Microscopic:  
*Cystic appearance.
 
=====Secretory=====
*Assoc. with brain edema; may have a worse outcome.
 
Microscopic:<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Com04/Com405-1-Diss.htm http://moon.ouhsc.edu/kfung/jty1/Com04/Com405-1-Diss.htm]. Accessed on: 12 October 2011.</ref>
*Eosinophilic intracytoplasmic inclusions that are CEA +ve and PAS +ve.
 
DDx:
*Metastatic mucinous adenocarcinoma.
 
=====Lymphoplasmacyte-rich=====
Microscopic:
*Lymphocytes.
*Plasma cells.
=====Metaplastic=====
*Much talked about... but very rare.
 
Microscopic:  
*Cartilage or bone formation.


====Grade II====
====Grade II====
48,536

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