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==Unusual forms of prostate cancer== | ==Unusual forms of prostate cancer== | ||
===Ductal adenocarcinoma=== | ===Ductal adenocarcinoma=== | ||
Features: | Features:<ref name=Ref_GUP88>{{Ref GUP|88}}</ref> | ||
* | *Pseudostratified (crowded appearing) columnar (or cigar-shaped) nuclei - '''key feature'''. | ||
**Vaguely resembles colonic adenocarcinoma. | **Vaguely resembles colonic adenocarcinoma. | ||
*Variable architecture: | |||
**Papillary. | |||
**Cribriform. | |||
**Single gland (large glands). | |||
**Endometrioid - vaguely looks like endometrial carcinoma (with back-to-back glands). | |||
Notes: | |||
*Usually seen in association with conventional (acinar) prostate adenocarcinoma. | *Usually seen in association with conventional (acinar) prostate adenocarcinoma. | ||
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*Usually associated with conventional (acinar) prostate adenocarcinoma. | *Usually associated with conventional (acinar) prostate adenocarcinoma. | ||
*Pale abundant cytoplasm - similar to normal prostate. | *Pale abundant cytoplasm - similar to normal prostate. | ||
===Prostate cancer with signet ring cells=== | |||
Features: | |||
*Signet ring cells - see ''[[basics]]'' article. | |||
===Sarcomatoid prostate carcinoma=== | |||
Features:<ref name=Ref_GUP80>{{Ref GUP|80}}</ref> | |||
*Biphasic tumour: | |||
*#Spindle cells (sarcomatous component). | |||
*#Glandular component (like conventional prostate carcinoma). | |||
==See also== | ==See also== |
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