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Difference between revisions of "Gynecologic cytopathology"
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Gynecologic cytopathology (view source)
Revision as of 23:07, 3 October 2011
, 23:07, 3 October 2011→Abnormal cells: more
m (→Actinomycetes) |
(→Abnormal cells: more) |
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| High-grade squamous intraepithelial lesion (HSIL) | | High-grade squamous intraepithelial lesion (HSIL) | ||
| | | Often single cells, may be groups | ||
| Well-circumscribed | | Well-circumscribed | ||
| Dark blue, '''scant''' - NC ratio ~ 1:2 | | Dark blue, '''scant''' - NC ratio ~ 1:2 | ||
| Large nucleus (3-4X IC nuc. - see ''Note 1''), '''nuc. membrane irregularities, clumping of coarse chromatin, dark nuc. staining''', +/- small nucleoli | | Large nucleus (3-4X IC nuc. - see ''Note 1''), '''nuc. membrane irregularities, clumping of coarse chromatin, dark nuc. staining''', +/- small nucleoli | ||
| DDx: squamous metaplasia, atrophy with atypia | | DDx: squamous metaplasia, atrophy with atypia | ||
|- | |||
| Atypical squamous cells of unknown significance (ASCUS) | |||
| Single cells/groups | |||
| Irregular or moderately-circumscribed | |||
| Blue, abundant cytoplasm | |||
| '''Moderately enlarged nucleus''' (~2.5-3.0X IC nuc.), minimal changes in nuclear membrane and chromatin | |||
| DDx: LSIL | |||
|- | |||
| Atypical squamous cells cannot exclude HSIL (ASC-H) | |||
| Often single cells, may be groups | |||
| Irregular or moderately-circumscribed | |||
| Blue, '''moderate-to-scant''' cytoplasm | |||
| '''Moderately enlarged nucleus''' (~1.5-2.0X IC nuc.), minimal changes in nuclear membrane and chromatin | |||
| DDx: HSIL, AIS | |||
|- | |- | ||
| Atypical glandular cell (AGC) | | Atypical glandular cell (AGC) | ||