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Difference between revisions of "Pediatric kidney tumours"
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*#Epithelial nodules. | *#Epithelial nodules. | ||
*#*Similar to [[metanephric adenoma]]. | *#*Similar to [[metanephric adenoma]]. | ||
==Mesoblastic nephroma== | |||
===General=== | |||
*Almost exclusively in infants. | |||
Subclassified: | |||
#Classic. | |||
#Cellular. | |||
#Mixed. | |||
===Gross=== | |||
*Renal sinus infiltration - common. | |||
===Microscopic=== | |||
====Classic==== | |||
Features:<ref name=Ref_WMSP284>{{Ref WMSP|284}}</ref> | |||
*Spindle cells in fascicles. | |||
*Infiltrative border. | |||
====Cellular==== | |||
Features:<ref name=Ref_WMSP284>{{Ref WMSP|284}}</ref> | |||
*Plump cells with vesicular nuclei. | |||
*Well-defined border. | |||
*Mitotically active. | |||
====Mixed==== | |||
*Like the name implies - both ''classic'' pattern and ''cellular'' pattern areas are present. | |||
===Molecular=== | |||
Cellular mesoblastic nephroma: | |||
*t(12:15)(p13;q25) ETV6/NTRK3. | |||
**Same [[translocation]] if found in ''[[infantile fibrosarcoma]]''. | |||
====Mixed==== | |||
Features:<ref name=Ref_WMSP284>{{Ref WMSP|284}}</ref> | |||
==See also== | ==See also== | ||