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Difference between revisions of "Prostate gland"
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→Atrophy: +inflammations
(→IHC of normal prostate: repl. ref.) |
(→Atrophy: +inflammations) |
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** Normal is age dependent - increases with age, usu. cut-off ~ 4 ng/mL. | ** Normal is age dependent - increases with age, usu. cut-off ~ 4 ng/mL. | ||
*HIFU = ''High Intensity Focused Ultrasound'' - an ablation procedure for prostate cancer.<ref>URL: [http://www.internationalhifu.com/what-is-hifu-mainmenu-132.html http://www.internationalhifu.com/what-is-hifu-mainmenu-132.html]. Accessed on: 15 June 2010.</ref> | *HIFU = ''High Intensity Focused Ultrasound'' - an ablation procedure for prostate cancer.<ref>URL: [http://www.internationalhifu.com/what-is-hifu-mainmenu-132.html http://www.internationalhifu.com/what-is-hifu-mainmenu-132.html]. Accessed on: 15 June 2010.</ref> | ||
==Acute inflammation== | |||
===General=== | |||
*A may lead to an increase in the PSA and prompt biopsy. | |||
===Microscopic=== | |||
Features: | |||
*[[Neutrophil]]s within the glands, between the epithelial cells ''or'' within the stroma - '''key feature'''. | |||
Note: | |||
*"Prostatitis" is considered a clinical diagnosis. | |||
**Cases are signed-out as "acute inflammation". | |||
***Some pathologists do not comment on the presence (or absence) of inflammation. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Acute_inflammation_of_prostate.jpg Prostate with acute inflammation (WC)]. | |||
==Chronic inflammation== | |||
===Chronic inflammation not otherwise specified=== | |||
====Common==== | |||
*Non-specific. | |||
*Etiology usu. not apparent on histomorphology. | |||
====Microscopic==== | |||
Features: | |||
*Lymphocytes within the glands, between the epithelial cells ''or'' within the stroma - '''key feature'''. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Inflammation_of_prostate.jpg Prostate with chronic inflammation (WC)]. | |||
===Granulomatous inflammation=== | |||
====General==== | |||
*Common. | |||
*Usu. secondary to BCG treatment of bladder cancer. | |||
DDx: | |||
*BCG treatment effect. | |||
*Infectious (tuberculosis, fungal). | |||
*Foreign body/traumatic (post-TURP). | |||
====Microscopic==== | |||
Features: | |||
*[[Granulomas]] in the stroma of the prostate. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Granulomatous_inflammation_of_bladder_neck.jpg Granulomatous inflammation of the prostate/bladder neck - low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Granulomatous_inflammation_of_bladder_neck_high_mag.jpg Granulomatous inflammation of the prostate/bladder neck - high mag. (WC)]. | |||
==Atrophy== | ==Atrophy== | ||