Difference between revisions of "Gastrointestinal tract polyps"

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==Juvenile polyp==
==Juvenile polyp==
*[[AKA]] ''retension polyp'' in adults.
===General===
===General===
*Referred to ''retension polyps'' in non-juveniles.
May be part of a syndrome:
May be part of a syndrome:
*[[Juvenile polyposis syndrome]] (JPS) - JPS article for criteria.
*[[Juvenile polyposis syndrome]] (JPS) - see JPS article for criteria.
*[[Cronkhite-Canada syndrome]].
*[[Cronkhite-Canada syndrome]].
*[[Cowden syndrome]].
*[[Cowden syndrome]].
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Notes:  
Notes:  
*Nuclear changes may be like those seen in adenomatous polyps.
*May have nuclear changes like those seen in adenomatous polyps.
*IHC can be used as an adjunct (p53, Ki-67).
 
**p53 mutations in dysplastic epithelium -- negative stain (normal).
DDx:
*Inflammatory polyp.


Images:  
Images:  
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*[http://commons.wikimedia.org/wiki/File:Gastric_juvenile_polyp_-_2_-_very_low_mag.jpg Juvenile polyp of the stomach - very low mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Gastric_juvenile_polyp_-_2_-_very_low_mag.jpg Juvenile polyp of the stomach - very low mag. (WC)].


DDx:
===IHC===
*Inflammatory polyp.
*Usually none.
 
Notes:
*IHC can be used if it is suspected to have dysplasia (p53, Ki-67).
**p53 mutations in dysplastic epithelium -- negative stain (normal).


==Peutz-Jeghers polyp==
==Peutz-Jeghers polyp==
48,874

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