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===Peutz-Jeghers polyp=== | ===Peutz-Jeghers polyp=== | ||
====Clinical/Epidemiology==== | ====Clinical/Epidemiology==== | ||
Features:<ref name=Ref_PBoD859/><ref> | Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/full/3880773a.html }}</ref> | ||
*Peutz-Jeghers syndrome is autosomal dominant. | *Peutz-Jeghers syndrome is autosomal dominant. | ||
*Altered gene: STK11. | *Altered gene: STK11. | ||
====Microscopy==== | ====Microscopy==== | ||
Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/ | Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/full/3880773a.html }}</ref> | ||
*Frond-like polyp with all three components of mucosa: | *Frond-like polyp with all three components of mucosa: | ||
*# Muscosal epithelium (melanotic mucosa, goblet cells). | *# Muscosal epithelium (melanotic mucosa, goblet cells). | ||
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Image: | Image: | ||
*[http://commons.wikimedia.org/wiki/File:Peutz-Jeghers_syndrome_polyp.jpg Peutz-Jeghers syndrome polyp (WC)]. | *[http://commons.wikimedia.org/wiki/File:Peutz-Jeghers_syndrome_polyp.jpg Peutz-Jeghers syndrome polyp (WC)]. | ||
*[http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f3.html Peutz-Jeghers polyp (nature.com)]. | |||
===Cowden disease=== | ===Cowden disease=== | ||
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