Difference between revisions of "Gastrointestinal tract polyps"

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===Peutz-Jeghers polyp===
===Peutz-Jeghers polyp===
====Clinical/Epidemiology====
====Clinical/Epidemiology====
Features:<ref name=Ref_PBoD859/><ref>[http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f4.html http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f4.html]</ref>
Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal  | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/full/3880773a.html }}</ref>
*Peutz-Jeghers syndrome is autosomal dominant.
*Peutz-Jeghers syndrome is autosomal dominant.
*Altered gene: STK11.
*Altered gene: STK11.


====Microscopy====  
====Microscopy====  
Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal  | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f4.html }}</ref>
Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal  | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/full/3880773a.html }}</ref>
*Frond-like polyp with all three components of mucosa:
*Frond-like polyp with all three components of mucosa:
*# Muscosal epithelium (melanotic mucosa, goblet cells).
*# Muscosal epithelium (melanotic mucosa, goblet cells).
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Image:
Image:
*[http://commons.wikimedia.org/wiki/File:Peutz-Jeghers_syndrome_polyp.jpg Peutz-Jeghers syndrome polyp (WC)].
*[http://commons.wikimedia.org/wiki/File:Peutz-Jeghers_syndrome_polyp.jpg Peutz-Jeghers syndrome polyp (WC)].
*[http://www.nature.com/modpathol/journal/v16/n4/fig_tab/3880773f3.html Peutz-Jeghers polyp (nature.com)].


===Cowden disease===
===Cowden disease===
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