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Difference between revisions of "Epidermal necrosis"
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→Staphylococcal scalded skin syndrome: more
| Line 66: | Line 66: | ||
*Abbreviated ''SSSS''. | *Abbreviated ''SSSS''. | ||
===General=== | ===General=== | ||
* | *Due to keratinocyte cell-cell adhesion loss in the superficial epidermis - caused by ''S. aureus''.<ref name=pmid17582744>{{Cite journal | last1 = Nishifuji | first1 = K. | last2 = Sugai | first2 = M. | last3 = Amagai | first3 = M. | title = Staphylococcal exfoliative toxins: "molecular scissors" of bacteria that attack the cutaneous defense barrier in mammals. | journal = J Dermatol Sci | volume = 49 | issue = 1 | pages = 21-31 | month = Jan | year = 2008 | doi = 10.1016/j.jdermsci.2007.05.007 | PMID = 17582744 }}</ref> | ||
Clinical: | Clinical: | ||
*Blisters | *Blisters | ||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=pmid17582744/> | Features:<ref name=pmid17582744/> | ||
* | *Superficial dermis separates from underlying tissue - looks artefactual. | ||
*Minimal/scant inflammation is typical.<ref>URL: [http://dermatlas.med.jhmi.edu/derm/display.cfm?ImageID=2105774586 http://dermatlas.med.jhmi.edu/derm/display.cfm?ImageID=2105774586]. Accessed on: 22 September 2011.</ref> | *Minimal/scant inflammation is typical.<ref>URL: [http://dermatlas.med.jhmi.edu/derm/display.cfm?ImageID=2105774586 http://dermatlas.med.jhmi.edu/derm/display.cfm?ImageID=2105774586]. Accessed on: 22 September 2011.</ref> | ||