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Difference between revisions of "Medical liver disease"
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Medical liver disease (view source)
Revision as of 14:25, 22 September 2011
, 14:25, 22 September 2011→Focal nodular hyperplasia
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==Focal nodular hyperplasia== | ==Focal nodular hyperplasia== | ||
*Abbreviated ''FNH''. | |||
===General=== | ===General=== | ||
*Not commonly seen by pathologists, as these are usually distinctive on medical imaging.<ref name=pmid11274535>{{Cite journal | last1 = Brancatelli | first1 = G. | last2 = Federle | first2 = MP. | last3 = Grazioli | first3 = L. | last4 = Blachar | first4 = A. | last5 = Peterson | first5 = MS. | last6 = Thaete | first6 = L. | title = Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients. | journal = Radiology | volume = 219 | issue = 1 | pages = 61-8 | month = Apr | year = 2001 | doi = | PMID = 11274535 }}</ref> | |||
*Not commonly seen by pathologists. | |||
*Benign lesions. | *Benign lesions. | ||
*Associated with oral contraceptive pill (OCP) use. | *Associated with oral contraceptive pill (OCP) use. | ||
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====Imaging==== | ====Imaging==== | ||
*FNH enhances on the arterial phase in triphasic imaging, i.e. triphasic CT or MRI.<ref name=emedicine_fnh>[http://emedicine.medscape.com/article/368377-overview http://emedicine.medscape.com/article/368377-overview]</ref> | *FNH enhances on the arterial phase in triphasic imaging, i.e. triphasic CT or MRI.<ref name=emedicine_fnh>[http://emedicine.medscape.com/article/368377-overview http://emedicine.medscape.com/article/368377-overview]</ref><ref name=pmid11274535>{{Cite journal | last1 = Brancatelli | first1 = G. | last2 = Federle | first2 = MP. | last3 = Grazioli | first3 = L. | last4 = Blachar | first4 = A. | last5 = Peterson | first5 = MS. | last6 = Thaete | first6 = L. | title = Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients. | journal = Radiology | volume = 219 | issue = 1 | pages = 61-8 | month = Apr | year = 2001 | doi = | PMID = 11274535 }}</ref> | ||
===Gross=== | ===Gross=== | ||
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*Well circumscribed, but no capsule. | *Well circumscribed, but no capsule. | ||
*Lighter than surrounding parenchyma, may be yellow. | *Lighter than surrounding parenchyma, may be yellow. | ||
*+/-Stellate central scar with thick vessels. | *+/-Stellate central scar with thick vessels. | ||
**Can be identified on medial imaging. | |||
Note: Usually a solitary lesion.<ref name=emedicine_fnh/> | Note: Usually a solitary lesion.<ref name=emedicine_fnh/> | ||
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DDx: | DDx: | ||
*Hepatic adenoma - may be difficult to distinguish, if no scar and no ductal proliferation.<ref>STC. 19 Jan 2009.</ref> | *Hepatic adenoma - may be difficult to distinguish, if no scar and no ductal proliferation.<ref>STC. 19 Jan 2009.</ref> | ||
*Cirrhosis. | *Cirrhosis - complete nodules | ||
**FNH has incomplete nodules. | |||
Images: | Images: | ||