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Difference between revisions of "Peripheral nerve sheath tumours"
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Peripheral nerve sheath tumours (view source)
Revision as of 13:42, 21 September 2011
, 13:42, 21 September 2011→Neurothekeoma: more
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=pmid17325474>{{cite journal |author=Hornick JL, Fletcher CD |title=Cellular neurothekeoma: detailed characterization in a series of 133 cases |journal=Am. J. Surg. Pathol. |volume=31 |issue=3 |pages=329–40 |year=2007 |month=March |pmid=17325474 |doi=10.1097/01.pas.0000213360.03133.89 |url=}}</ref> | Features:<ref name=pmid17325474>{{cite journal |author=Hornick JL, Fletcher CD |title=Cellular neurothekeoma: detailed characterization in a series of 133 cases |journal=Am. J. Surg. Pathol. |volume=31 |issue=3 |pages=329–40 |year=2007 |month=March |pmid=17325474 |doi=10.1097/01.pas.0000213360.03133.89 |url=}}</ref> | ||
* | *Superficial dermal lesion: | ||
*+/-Inflammation around lesion. | **Usu. lobulated or micronodular architecture - '''key feature'''. | ||
***+/-Focal sheeting. | |||
**Spindle/epithelioid morphology with pale eosinophilic cytoplasm - '''key feature'''. | |||
**+/-Inflammation around lesion. | |||
**+/-Surrounded by collagen. | |||
Notes: | Notes: | ||
*No atypia. | *No atypia. | ||
*Mitoses rare/none. | *Mitoses rare/none. | ||
*Often poorly circumscribed. | |||
Subtypes:<ref name=pmid10555009>{{cite journal |author=Wang AR, May D, Bourne P, Scott G |title=PGP9.5: a marker for cellular neurothekeoma |journal=Am. J. Surg. Pathol. |volume=23 |issue=11 |pages=1401–7 |year=1999 |month=November |pmid=10555009 |doi= |url=}}</ref> | Subtypes:<ref name=pmid10555009>{{cite journal |author=Wang AR, May D, Bourne P, Scott G |title=PGP9.5: a marker for cellular neurothekeoma |journal=Am. J. Surg. Pathol. |volume=23 |issue=11 |pages=1401–7 |year=1999 |month=November |pmid=10555009 |doi= |url=}}</ref> | ||