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Difference between revisions of "Dermatologic neoplasms"
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Dermatologic neoplasms (view source)
Revision as of 04:19, 21 September 2011
, 04:19, 21 September 2011→Keratoacanthoma
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==Keratoacanthoma== | ==Keratoacanthoma== | ||
*Abbreviated ''KA''. | *Abbreviated ''KA''. | ||
===General=== | |||
*Generally considered to be benign. | *Generally considered to be benign. | ||
**Rare reports of metastases suggesting it may be a form of squamous cell carcinoma.<ref>{{cite journal |author=Mandrell JC, Santa Cruz D |title=Keratoacanthoma: hyperplasia, benign neoplasm, or a type of squamous cell carcinoma? |journal=Semin Diagn Pathol |volume=26 |issue=3 |pages=150–63 |year=2009 |month=August |pmid=20043514 |doi= |url=}}</ref> | **Rare reports of metastases suggesting it may be a form of squamous cell carcinoma.<ref>{{cite journal |author=Mandrell JC, Santa Cruz D |title=Keratoacanthoma: hyperplasia, benign neoplasm, or a type of squamous cell carcinoma? |journal=Semin Diagn Pathol |volume=26 |issue=3 |pages=150–63 |year=2009 |month=August |pmid=20043514 |doi= |url=}}</ref> | ||
===Clinical=== | ====Clinical==== | ||
*May grow rapidly (weeks or months) then involute. | *May grow rapidly (weeks or months) then involute. | ||
*Main DDx is [[squamous cell carcinoma]]. | *Main DDx is [[squamous cell carcinoma]]. | ||
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref>{{Ref Klatt|378}}</ref> | Features:<ref name=Ref_Klatt378>{{Ref Klatt|378}}</ref> | ||
*Expansion of stratum spinosum - pushing tongue-like downward growth of epidermis into the dermis. | *Expansion of stratum spinosum - pushing tongue-like downward growth of epidermis into the dermis. | ||
*Keratin collection (keratin plug) at the center of lesion-superficial aspect. | *Keratin collection (keratin plug) at the center of lesion-superficial aspect. | ||