Difference between revisions of "Non-malignant skin disease"

Jump to navigation Jump to search

Non-malignant skin disease (view source)

Revision as of 20:03, 20 September 2011

3,713 bytes removed ,  20:03, 20 September 2011
→‎Less common: mv to dermal neoplasms
(→‎Less common: mv to dermal neoplasms)
Line 403: Line 403:
**''Molluscum bodies'' are only the epidermis - an uncommon place to find SRCs without finding them elsewhere.
**''Molluscum bodies'' are only the epidermis - an uncommon place to find SRCs without finding them elsewhere.
*The granular eosinophilic cytoplasm represents accumulated virons.
*The granular eosinophilic cytoplasm represents accumulated virons.
==Syringoma==
===General===
*Benign sweat duct tumour.
*Eccrine differentiation.
*Usually close to lower eyelid.<ref>{{Ref PBoD8|1177}}</ref>
===Microscopic===
Features:<ref>URL: [http://emedicine.medscape.com/article/1059871-diagnosis http://emedicine.medscape.com/article/1059871-diagnosis]. Accessed on: 12 May 2010.</ref>
*Proliferation of benign ducts with lined by a bilayer (as in normal sweat ducts) with abnormal architecture:
**Tadpole like appearing ducts.
Images:
*[http://www.flickr.com/photos/euthman/2329061316/ Syringoma (flickr.com)].
*[http://dermatology.cdlib.org/144/tumors/axillary_syringoma/2.jpg Syringoma (dermatology.cdlib.org)].<ref>{{Cite journal  | last1 = Nosrati | first1 = N. | last2 = Coleman | first2 = NM. | last3 = Hsu | first3 = S. | title = Axillary syringomas. | journal = Dermatol Online J | volume = 14 | issue = 4 | pages = 13 | month =  | year = 2008 | doi =  | PMID = 18627735 |URL = http://dermatology.cdlib.org/144/tumors/axillary_syringoma/hsu.html}}</ref>
==Chondroid syringoma==
*Used to be called ''mixed tumour of skin''.<ref name=pmid19693940>{{Cite journal  | last1 = Kumar | first1 = B. | title = Chondroid syringoma diagnosed by fine needle aspiration cytology. | journal = Diagn Cytopathol | volume = 38 | issue = 1 | pages = 38-40 | month = Jan | year = 2010 | doi = 10.1002/dc.21159 | PMID = 19693940 }}</ref>
===General===
*Mixed apocrine & eccrine tumour of skin, usu. in the head & neck<ref name=pmid19693940/>, esp. nose and cheek.<ref name=pmid19633639/>
*May be in major and minor salivary glands.<ref name=pmid19633639>{{Cite journal  | last1 = Rauso | first1 = R. | last2 = Santagata | first2 = M. | last3 = Tartaro | first3 = G. | last4 = Filipi | first4 = M. | last5 = Colella | first5 = G. | title = Chondroid syringoma: a rare tumor of orofacial region. | journal = Minerva Stomatol | volume = 58 | issue = 7-8 | pages = 383-8 | month =  | year =  | doi =  | PMID = 19633639 }}</ref>
===Microscopic===
Features:
*Mix tumour with:<ref name=pmid19693940/>
*#Epithelial component:
*#*Nests of cells with:
*#**Moderate dull eosinophilic cytoplasm.
*#**Round/ovoid nuclei with nucleoli.
*#Mesenchymal component:
*#*Chondromyxoid stroma.
==Dermal cylindroma==
===General===
*Benign skin lesion.
*Should not be confused with ''cylindroma'' ([[adenoid cystic carcinoma]]).
===Microscopic===
Features:
*Nests of cells that are surrounded by hyaline (i.e. glassy, eosinophilic, acellular) material.
DDx:
*[[Eccrine spiradenoma]].
Images:
*[http://commons.wikimedia.org/wiki/File:Dermal_cylindroma_intermed_mag.jpg Dermal cylindroma (WC)].
*[http://commons.wikimedia.org/wiki/File:Dermal_cylindroma_intermed_mag_deep.jpg Dermal cylindroma - high mag. (WC)].
==Keratoacanthoma==
*Abbreviated ''KA''.
*Generally considered to be benign.
**Rare reports of metastases suggesting it may be a form of squamous cell carcinoma.<ref>{{cite journal |author=Mandrell JC, Santa Cruz D |title=Keratoacanthoma: hyperplasia, benign neoplasm, or a type of squamous cell carcinoma? |journal=Semin Diagn Pathol |volume=26 |issue=3 |pages=150–63 |year=2009 |month=August |pmid=20043514 |doi= |url=}}</ref>
===Clinical===
*May grow rapidly (weeks or months) then involute.
*Main DDx is [[squamous cell carcinoma]].
*Exophytic lesion, well-circumscribed.
===Microscopic===
Features:<ref>{{Ref Klatt|378}}</ref>
*Expansion of stratum spinosum - pushing tongue-like downward growth of epidermis into the dermis.
*Keratin collection (keratin plug) at the center of lesion-superficial aspect.
*Cells have glassy pink cytoplasm.
*Minimal/no nuclear atypia.
Image:
*[http://commons.wikimedia.org/wiki/File:Skin_keratoacanthoma_whole_slide.jpg Keratocanthoma (WC).]


==Superficial dermal infiltrates==
==Superficial dermal infiltrates==
Michael
48,830

edits

Retrieved from "https://librepathology.org/wiki/Special:MobileDiff/7726"

Navigation menu