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Difference between revisions of "Prostate gland"
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→Prostate: re-order
m (→Seminal vesicles: inclusions) |
(→Prostate: re-order) |
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*Glands have two cell layers (similar to glands in breast). | *Glands have two cell layers (similar to glands in breast). | ||
**Second cell layer may be difficult to see (like in breast). | **Second cell layer may be difficult to see (like in breast). | ||
*Epithelium in glands | *Epithelium in glands is "folded" or "tufted". | ||
**Very important - helps on differentiate from Gleason pattern 3. | **Very important - helps on differentiate from Gleason pattern 3. | ||
*Luminal epithelium often clear. | *Luminal epithelium often clear. | ||
| Line 21: | Line 21: | ||
**Very common. | **Very common. | ||
**These should be differentiated from ''eosinophilic proteinaceous debris'' - which is associated with cancer. | **These should be differentiated from ''eosinophilic proteinaceous debris'' - which is associated with cancer. | ||
====IHC of normal prostate==== | ====IHC of normal prostate==== | ||
Normal prostate: | Normal prostate: | ||
*AMACR- | *AMACR -ve (mark epithelial cells). | ||
*p63 +ve, HMWCK +ve (mark basal cells). | |||
*PSA +ve, PSAP +ve. | |||
===Male accessory glands=== | |||
*Mucinous glands at the apex of the prostate = ''Cowper's gland'' (AKA ''bulbourethral gland''), resemble (mucinous) [[salivary gland]]s.<ref>PR. September 2009.</ref> | |||
===Seminal vesicles=== | ===Seminal vesicles=== | ||