48,873
edits
Difference between revisions of "Vasculitides"
Jump to navigation
Jump to search
m
→Giant cell arteritis
(→Microscopic: wikify) |
|||
| Line 84: | Line 84: | ||
=Vasculitides= | =Vasculitides= | ||
The follow section has information specific to the individual types of vasculitis. | The follow section has information specific to the individual types of vasculitis. | ||
==Small vessel leukocytoclastic vasculitis== | |||
*Abbreviated ''LCV''. | |||
===General=== | |||
*Most common cutaneous vasculitis.<ref name=pmid18948765>{{Cite journal | last1 = Brinster | first1 = NK. | title = Dermatopathology for the surgical pathologist: a pattern-based approach to the diagnosis of inflammatory skin disorders (part II). | journal = Adv Anat Pathol | volume = 15 | issue = 6 | pages = 350-69 | month = Nov | year = 2008 | doi = 10.1097/PAP.0b013e31818b1ac6 | PMID = 18948765 }}</ref> | |||
Clinical: | |||
*Palpable purpura, usu. lower extremity. | |||
Has a broad DDx:<ref name=pmid18948765/> | |||
*Infectious: | |||
**Bacterial. | |||
**Viral. | |||
**Fungal. | |||
*Vasculitic disorders: | |||
**ANCA mediated vasculitides: | |||
***[[Wegener granulomatosis]]. | |||
***[[Churg-Strauss syndrome]]. | |||
**Henoch–Schönlein purpura. | |||
**Urticarial vasculitis. | |||
*Other: | |||
**Connective tissue disease. | |||
**Cryoglobulinemia - may be due to [[multiple myeloma]], [[hepatitis C]]; have intravascular thrombi. | |||
**Paraneoplastic. | |||
**Drugs. | |||
===Microscopic=== | |||
Features:<ref name=pmid18948765/> | |||
*Small upper dermis vessels with: | |||
*#Neutrophils. | |||
*#*Fragmentation of neutrophils (leukocytoclasia). | |||
*#Vessel damage: fibrin deposition (bright pink acellular stuff). | |||
Image: | |||
*[http://www.ancavasculitis.com/biopsy.php LCA (ancavasculitis.com)]. | |||
==Giant cell arteritis== | ==Giant cell arteritis== | ||