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Difference between revisions of "Lymph node pathology"
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This article deals with '''lymph node pathology'''. An introduction to the lymph node is in the ''[[lymph nodes]]'' article. | This article deals with '''lymph node pathology'''. An introduction to the lymph node is in the ''[[lymph nodes]]'' article. | ||
==Progressive transformation of germinal centers== | |||
===General=== | |||
*Abbreviated as ''PTGC''. | |||
*Benign. | |||
*Classically in younger patients. | |||
*Associated with Hodgkin's lymphoma - non-classic type (nodular lymphocyte predominant Hodgkin's lymphoma). | |||
===Micrograph=== | |||
Features: | |||
*Large germinal centers - focally. | |||
**No mass lesions. | |||
==Kikuchi disease== | ==Kikuchi disease== | ||
===General=== | ===General=== | ||
*AKA ''histiocytic necrotising lymphadenitis'' (HNL) | *AKA ''histiocytic necrotising lymphadenitis'' (HNL),<ref name="pmid15570824">{{cite journal |author=Kaushik V, Malik TH, Bishop PW, Jones PH |title=Histiocytic necrotising lymphadenitis (Kikuchi's disease): a rare cause of cervical lymphadenopathy |journal=Surgeon |volume=2 |issue=3 |pages=179–82 |year=2004 |month=June |pmid=15570824 |doi= |url=}}</ref> and ''Kikuchi-Fujimoto disease''. | ||
*Rare disease that may mimic cancer, esp. lymphoma. | *Rare disease that may mimic cancer, esp. lymphoma. | ||
**May cause fever & systemic symptoms.<ref name=pmid20121621>{{cite journal |author=Hutchinson CB, Wang E |title=Kikuchi-Fujimoto disease |journal=Arch. Pathol. Lab. Med. |volume=134 |issue=2 |pages=289–93 |year=2010 |month=February |pmid=20121621 |doi= |url=}}</ref> | **May cause fever & systemic symptoms.<ref name=pmid20121621>{{cite journal |author=Hutchinson CB, Wang E |title=Kikuchi-Fujimoto disease |journal=Arch. Pathol. Lab. Med. |volume=134 |issue=2 |pages=289–93 |year=2010 |month=February |pmid=20121621 |doi= |url=}}</ref> | ||