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Difference between revisions of "Thymus"
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*Location: anterior mediastinum. | *Location: anterior mediastinum. | ||
*Important for development of the immune system. | *Important for development of the immune system. | ||
*May contain within it parathyroid.<ref>PBoD | *May contain within it parathyroid.<ref>{{Ref PBoD|706}}</ref> | ||
==Histology== | ==Histology== | ||
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*Hassall's corpusle (thymic corpusle). | *Hassall's corpusle (thymic corpusle). | ||
**Round eosinophilic thingy. | **Round eosinophilic thingy. | ||
**Thought to arise from medullary epithelial cells (see ''cell types'').<ref>PBoD | **Thought to arise from medullary epithelial cells (see ''cell types'').<ref>{{Ref PBoD|706}}</ref> | ||
===Cell types=== | ===Cell types=== | ||
Cells of the thymus (short version): | Cells of the thymus (short version): | ||
#Cortical epithelial cells.<ref>PBoD | #Cortical epithelial cells.<ref>{{Ref PBoD|706}}</ref> | ||
#*Epithelioid. | #*Epithelioid. | ||
#*Abundant cytoplasm. | #*Abundant cytoplasm. | ||
#*Pale nuclei with small nucleoli. | #*Pale nuclei with small nucleoli. | ||
#Medullary epithelial cells.<ref>PBoD | #Medullary epithelial cells.<ref>{{Ref PBoD|706}}</ref> | ||
#*Spindle morphology. | #*Spindle morphology. | ||
#*Scant cytoplasm. | #*Scant cytoplasm. | ||
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*AKA ''thymic follicular hyperplasia''. | *AKA ''thymic follicular hyperplasia''. | ||
Features:<ref>PBoD | Features:<ref>{{Ref PBoD|707}}</ref> | ||
*Follicular centres in the thymus. | *Follicular centres in the thymus. | ||
Associations:<ref>PBoD | Associations:<ref>{{Ref PBoD|707-8}}</ref> | ||
*Myasthenia gravis. | *Myasthenia gravis. | ||
*Graves' diseases. | *Graves' diseases. | ||
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IHC: | IHC: | ||
*CD5 +ve.<ref>PBoD | *CD5 +ve.<ref>{{Ref PBoD|708}}</ref> | ||
==Staging== | ==Staging== | ||