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Difference between revisions of "Cancer"
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This article deals with general concepts in cancer. Specific forms of cancer are described by the site from which they arise. This article discusses ''cancers of unknown primary''. | This article deals with general concepts in cancer. Specific forms of cancer are described by the site from which they arise. This article discusses ''cancers of unknown primary''. | ||
==Definition== | ==Definition of cancer== | ||
* | Robbins definition of cancer:<ref name=Ref_PCPBoD8_145>{{Ref PCPBoD8|145}}</ref> | ||
*Tumour with the capacity to: | |||
*#Invade (infiltrate) and destroy adjacent tissue. | |||
*#Spread to other sites (metastasize). | |||
Notes: | |||
#Tumour = abnormal mass of tissue.<ref name=Ref_PCPBoD8_145>{{Ref PCPBoD8|145}}</ref> | |||
#*Neoplasm = literally "new growth"; used interchangeably with ''tumour''.<ref name=Ref_PCPBoD8_145>{{Ref PCPBoD8|145}}</ref> | |||
===Tumours=== | |||
Tumours ''per Robbins''<ref name=Ref_PCPBoD8_145>{{Ref PCPBoD8|145}}</ref> consist of: | |||
#Clonal expansions. | |||
#Stromal components - controlled by the clonal component. | |||
== | ==Clinical features of cancer== | ||
*Uncontrolled growth. | *Uncontrolled growth. | ||
*Direct invasion. | *Direct invasion/destruction of tissue. | ||
*Metastases. | *Metastases. | ||