Difference between revisions of "Kidney tumours"

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229 bytes added ,  18:43, 7 September 2011
→‎IHC: more
(→‎IHC: more)
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DDx:
DDx:
*May appear similar to oncotyoma -- particularily the eosinophilic variant.
*May appear similar to oncotyoma -- particularily the eosinophilic variant.
**IHC: CK7: chromophobe = cell membrane CK7+; oncoctyoma = patchy cytoplasmic +ve
**A comparison based on histomorphology: ''[[Kidney_tumours#Tabular_comparison_of_oncocytoma_and_chromophobe_RCC|Tabular comparison between ChRCC & oncocytoma]]''.
***No perinuclear clearing in oncocytoma.
**IHC may be useful to differentiate (CK7: oncocytoma = cytoplasm +ve, chromophobe = cell membrane +ve).
*Classic ChRCC may be challenging to differentiate from clear cell RCC.
*Classic ChRCC may be challenging to differentiate from clear cell RCC.
**Perinuclear clearing is ''not'' seen in clear cell RCC.
**Perinuclear clearing is ''not'' seen in clear cell RCC.
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